STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ABC2897Sodium:dicarboxylate symporter; Mediates uptake of L-cystine, the oxidized form of L- cysteine; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (465 aa)    
Predicted Functional Partners:
cysI
Sulfite reductase flavoprotein subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
   
  
 0.785
cysJ
Sulfite reductase hemoprotein beta subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
   
  
 0.690
cysC
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
   
    0.638
ABC1944
Cysteine synthase.
   
  
 0.549
braB
Branched-chain amino acid transport system carrier protein BraB; Component of the transport system for branched-chain amino acids.
  
   
 0.506
luxS
S-ribosylhomocysteinase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
  
  
 0.491
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
      
 0.460
ABC2896
Conserved hypothetical protein.
       0.460
ABC1227
Sulfate ABC transporter permease; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
   
    0.438
cysK
Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
   
  
 0.428
Your Current Organism:
Bacillus clausii
NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16
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