ABC2952 protein (Bacillus clausii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ABC2952

Na+:H+ antiporter. (545 aa)

Predicted Functional Partners:

ABC2953

0.516

ABC0938

0.463

ABC1961

0.462

dfrA

0.457

ABC2957

0.457

thyB

0.454

ABC2998

0.434

ABC2956

0.424

ABC3931

0.421

ABC3451

0.419

Your Current Organism:

Bacillus clausii

NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABC0938	ABC2952	ABC0938	ABC2952	Na+:H+ antiporter.	Na+:H+ antiporter.	0.463
ABC1961	ABC2952	ABC1961	ABC2952	SNF family sodium-dependent transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	Na+:H+ antiporter.	0.462
ABC2952	ABC0938	ABC2952	ABC0938	Na+:H+ antiporter.	Na+:H+ antiporter.	0.463
ABC2952	ABC1961	ABC2952	ABC1961	Na+:H+ antiporter.	SNF family sodium-dependent transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.462
ABC2952	ABC2953	ABC2952	ABC2953	Na+:H+ antiporter.	Conserved hypothetical protein.	0.516
ABC2952	ABC2956	ABC2952	ABC2956	Na+:H+ antiporter.	Conserved hypothetical protein.	0.424
ABC2952	ABC2957	ABC2952	ABC2957	Na+:H+ antiporter.	5'-nucleotidase; Belongs to the 5'-nucleotidase family.	0.457
ABC2952	ABC2998	ABC2952	ABC2998	Na+:H+ antiporter.	Conserved hypothetical protein.	0.434
ABC2952	ABC3451	ABC2952	ABC3451	Na+:H+ antiporter.	Na+:H+-dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.	0.419
ABC2952	ABC3931	ABC2952	ABC3931	Na+:H+ antiporter.	Conserved hypothetical protein.	0.421
ABC2952	dfrA	ABC2952	ABC2954	Na+:H+ antiporter.	Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.	0.457
ABC2952	thyB	ABC2952	ABC2955	Na+:H+ antiporter.	Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.	0.454
ABC2953	ABC2952	ABC2953	ABC2952	Conserved hypothetical protein.	Na+:H+ antiporter.	0.516
ABC2953	ABC2956	ABC2953	ABC2956	Conserved hypothetical protein.	Conserved hypothetical protein.	0.696
ABC2953	ABC2957	ABC2953	ABC2957	Conserved hypothetical protein.	5'-nucleotidase; Belongs to the 5'-nucleotidase family.	0.636
ABC2953	dfrA	ABC2953	ABC2954	Conserved hypothetical protein.	Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.	0.716
ABC2953	thyB	ABC2953	ABC2955	Conserved hypothetical protein.	Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.	0.680
ABC2956	ABC2952	ABC2956	ABC2952	Conserved hypothetical protein.	Na+:H+ antiporter.	0.424
ABC2956	ABC2953	ABC2956	ABC2953	Conserved hypothetical protein.	Conserved hypothetical protein.	0.696
ABC2956	ABC2957	ABC2956	ABC2957	Conserved hypothetical protein.	5'-nucleotidase; Belongs to the 5'-nucleotidase family.	0.748