node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABC3042 | ABC3392 | ABC3042 | ABC3392 | N-acetyltransferase domain-containing protein; Probable gene remnant. Similar to the C-terminal region of conserved hypothetical protein. | NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.900 |
ABC3042 | argB | ABC3042 | ABC2556 | N-acetyltransferase domain-containing protein; Probable gene remnant. Similar to the C-terminal region of conserved hypothetical protein. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.904 |
ABC3042 | argJ | ABC3042 | ABC2557 | N-acetyltransferase domain-containing protein; Probable gene remnant. Similar to the C-terminal region of conserved hypothetical protein. | Bifunctional arginine biosynthesis protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.906 |
ABC3042 | gudB | ABC3042 | ABC1862 | N-acetyltransferase domain-containing protein; Probable gene remnant. Similar to the C-terminal region of conserved hypothetical protein. | NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.900 |
ABC3042 | hisA | ABC3042 | ABC3045 | N-acetyltransferase domain-containing protein; Probable gene remnant. Similar to the C-terminal region of conserved hypothetical protein. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | 0.551 |
ABC3042 | hisB | ABC3042 | ABC3047 | N-acetyltransferase domain-containing protein; Probable gene remnant. Similar to the C-terminal region of conserved hypothetical protein. | Imidazoleglycerol-phosphate dehydratase. | 0.539 |
ABC3042 | hisF | ABC3042 | ABC3044 | N-acetyltransferase domain-containing protein; Probable gene remnant. Similar to the C-terminal region of conserved hypothetical protein. | Imidazole glycerol phosphate synthase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.537 |
ABC3042 | hisG | ABC3042 | ABC3049 | N-acetyltransferase domain-containing protein; Probable gene remnant. Similar to the C-terminal region of conserved hypothetical protein. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.534 |
ABC3042 | hisH | ABC3042 | ABC3046 | N-acetyltransferase domain-containing protein; Probable gene remnant. Similar to the C-terminal region of conserved hypothetical protein. | Imidazole glycerol phosphate synthase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.542 |
ABC3042 | hisI | ABC3042 | ABC3043 | N-acetyltransferase domain-containing protein; Probable gene remnant. Similar to the C-terminal region of conserved hypothetical protein. | Bifunctional histidine biosynthesis protein HisJ; phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. | 0.549 |
ABC3392 | ABC3042 | ABC3392 | ABC3042 | NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | N-acetyltransferase domain-containing protein; Probable gene remnant. Similar to the C-terminal region of conserved hypothetical protein. | 0.900 |
ABC3392 | argJ | ABC3392 | ABC2557 | NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Bifunctional arginine biosynthesis protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.912 |
ABC3392 | gudB | ABC3392 | ABC1862 | NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.918 |
argB | ABC3042 | ABC2556 | ABC3042 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | N-acetyltransferase domain-containing protein; Probable gene remnant. Similar to the C-terminal region of conserved hypothetical protein. | 0.904 |
argB | argJ | ABC2556 | ABC2557 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Bifunctional arginine biosynthesis protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.999 |
argB | hisA | ABC2556 | ABC3045 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | 0.529 |
argB | hisB | ABC2556 | ABC3047 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Imidazoleglycerol-phosphate dehydratase. | 0.557 |
argB | hisF | ABC2556 | ABC3044 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Imidazole glycerol phosphate synthase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.571 |
argB | hisG | ABC2556 | ABC3049 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.527 |
argB | hisH | ABC2556 | ABC3046 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Imidazole glycerol phosphate synthase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.550 |