STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABC3212Conserved hypothetical protein. (114 aa)    
Predicted Functional Partners:
hisI
Bifunctional histidine biosynthesis protein HisJ; phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family.
   
  
 0.824
birA
Bifunctional biotin biosynthesis protein BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
    0.813
ABC1868
5,10-methylenetetrahydrofolate reductase.
 
  
 0.544
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.487
ABC3213
Sugar ABC transporter permease.
       0.459
ABC3214
Sugar ABC transporter permease.
       0.445
ABC3423
Cell surface protein.
  
     0.438
metS
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.432
ABC2105
5'-3' exonuclease.
     
 0.409
polA
DNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.409
Your Current Organism:
Bacillus clausii
NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.