STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
isdGConserved hypothetical protein; Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the biliverdin in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron; Belongs to the antibiotic biosynthesis monooxygenase family. Heme-degrading monooxygenase IsdG subfamily. (107 aa)    
Predicted Functional Partners:
ABC1946
Conserved hypothetical protein.
  
 
0.937
ABC3912
Conserved hypothetical protein; May function as heme-dependent peroxidase.
  
  
 0.924
ABC1472
Conserved hypothetical protein.
     
 0.913
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
    
  0.904
ctaB
Cytochrome oxidase assembly factor; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
     
  0.900
ABC3424
Cell surface protein.
 
  
 0.896
ABC3423
Cell surface protein.
 
  
 0.855
ABC3427
Fe3+-siderophore ABC transporter substrate-binding protein.
 
  
 0.792
ABC3422
cobalamin/Fe3+-siderophore ABC transporter substrate-binding protein.
 
  
 0.722
ABC3419
Conserved hypothetical protein.
 
  
 0.706
Your Current Organism:
Bacillus clausii
NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.