Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABC3446Hypothetical protein. (512 aa)    
Predicted Functional Partners:
ABC1939
Acetyltransferase.
  
     0.730
ABC3376
Conserved hypothetical protein.
  
     0.690
ABC3964
Conserved hypothetical protein.
  
     0.608
ABC3057
Conserved hypothetical protein.
  
     0.597
hemN
Oxygen-independent coproporphyrinogen oxidase III; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
     0.487
ABC3664
Outer surface protein.
  
    0.441
ABC3375
Two-component sensor histidine kinase.
  
    0.432
ABC3374
Two-component response regulator.
  
     0.406
ABC2381
Conserved hypothetical protein; Belongs to the UPF0342 family.
  
     0.400
Your Current Organism:
Bacillus clausii
NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16
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