spoIIID protein (Bacillus clausii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

spoIIID

Stage III sporulation protein D. (95 aa)

Predicted Functional Partners:

spoVT

0.922

spoIIIAE

0.918

spoIIR

0.903

spoIIIAC

0.897

spoIIAB

0.891

spoIIGA

0.889

spoIVA

0.854

sigK

0.852

gerAA

0.827

spoIIIAA

0.820

Your Current Organism:

Bacillus clausii

NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
gerAA	sigK	ABC3837	ABC1617	Sopre germination protein.	DNA-directed RNA polymerase sigma-27 factor sigma-K; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.746
gerAA	spoIIAB	ABC3837	ABC1794	Sopre germination protein.	Stage II sporulation protein AB; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.	0.763
gerAA	spoIIGA	ABC3837	ABC2352	Sopre germination protein.	Sporulation sigma-E factor processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.	0.558
gerAA	spoIIIAA	ABC3837	ABC2478	Sopre germination protein.	Stage III sporulation protein AA.	0.662
gerAA	spoIIIAC	ABC3837	ABC2476	Sopre germination protein.	Stage III sporulation protein AC.	0.689
gerAA	spoIIIAE	ABC3837	ABC2474	Sopre germination protein.	Stage III sporulation protein AE.	0.688
gerAA	spoIIID	ABC3837	ABC3842	Sopre germination protein.	Stage III sporulation protein D.	0.827
gerAA	spoIIR	ABC3837	ABC3872	Sopre germination protein.	Stage II sporulation protein R.	0.773
gerAA	spoIVA	ABC3837	ABC1882	Sopre germination protein.	Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.	0.769
gerAA	spoVT	ABC3837	ABC0084	Sopre germination protein.	Transcriptional regulator stage V sporulation protein T.	0.767
sigK	gerAA	ABC1617	ABC3837	DNA-directed RNA polymerase sigma-27 factor sigma-K; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Sopre germination protein.	0.746
sigK	spoIIAB	ABC1617	ABC1794	DNA-directed RNA polymerase sigma-27 factor sigma-K; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Stage II sporulation protein AB; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.	0.764
sigK	spoIIGA	ABC1617	ABC2352	DNA-directed RNA polymerase sigma-27 factor sigma-K; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Sporulation sigma-E factor processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.	0.635
sigK	spoIIIAA	ABC1617	ABC2478	DNA-directed RNA polymerase sigma-27 factor sigma-K; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Stage III sporulation protein AA.	0.671
sigK	spoIIIAC	ABC1617	ABC2476	DNA-directed RNA polymerase sigma-27 factor sigma-K; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Stage III sporulation protein AC.	0.456
sigK	spoIIIAE	ABC1617	ABC2474	DNA-directed RNA polymerase sigma-27 factor sigma-K; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Stage III sporulation protein AE.	0.563
sigK	spoIIID	ABC1617	ABC3842	DNA-directed RNA polymerase sigma-27 factor sigma-K; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Stage III sporulation protein D.	0.852
sigK	spoIIR	ABC1617	ABC3872	DNA-directed RNA polymerase sigma-27 factor sigma-K; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Stage II sporulation protein R.	0.727
sigK	spoIVA	ABC1617	ABC1882	DNA-directed RNA polymerase sigma-27 factor sigma-K; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.	0.771
sigK	spoVT	ABC1617	ABC0084	DNA-directed RNA polymerase sigma-27 factor sigma-K; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Transcriptional regulator stage V sporulation protein T.	0.741