tdk protein (Bacillus clausii) - STRING interaction network

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Score

tdk

Thymidine kinase. (192 aa)

Predicted Functional Partners:

thyB

0.979

ABC2847

0.958

pdp

0.955

tmk

0.947

comEB

0.927

ABC0477

0.917

cdd

0.917

ABC0966

0.915

maf

0.900

udk

0.834

Your Current Organism:

Bacillus clausii

NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABC0477	ABC0966	ABC0477	ABC0966	Hypothetical protein.	Nucleotidase; Belongs to the 5'-nucleotidase family.	0.909
ABC0477	cdd	ABC0477	ABC1680	Hypothetical protein.	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	0.900
ABC0477	pdp	ABC0477	ABC1784	Hypothetical protein.	Pyrimidine-nucleoside phosphorylase.	0.941
ABC0477	tdk	ABC0477	ABC3877	Hypothetical protein.	Thymidine kinase.	0.917
ABC0477	udk	ABC0477	ABC1598	Hypothetical protein.	Uridine kinase.	0.913
ABC0966	ABC0477	ABC0966	ABC0477	Nucleotidase; Belongs to the 5'-nucleotidase family.	Hypothetical protein.	0.909
ABC0966	ABC2847	ABC0966	ABC2847	Nucleotidase; Belongs to the 5'-nucleotidase family.	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	0.903
ABC0966	cdd	ABC0966	ABC1680	Nucleotidase; Belongs to the 5'-nucleotidase family.	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	0.909
ABC0966	comEB	ABC0966	ABC1647	Nucleotidase; Belongs to the 5'-nucleotidase family.	Late competence protein ComEB.	0.900
ABC0966	maf	ABC0966	ABC2616	Nucleotidase; Belongs to the 5'-nucleotidase family.	Septum formation protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.	0.900
ABC0966	pdp	ABC0966	ABC1784	Nucleotidase; Belongs to the 5'-nucleotidase family.	Pyrimidine-nucleoside phosphorylase.	0.900
ABC0966	tdk	ABC0966	ABC3877	Nucleotidase; Belongs to the 5'-nucleotidase family.	Thymidine kinase.	0.915
ABC0966	thyB	ABC0966	ABC2955	Nucleotidase; Belongs to the 5'-nucleotidase family.	Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.	0.904
ABC0966	tmk	ABC0966	ABC0050	Nucleotidase; Belongs to the 5'-nucleotidase family.	Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.	0.909
ABC0966	udk	ABC0966	ABC1598	Nucleotidase; Belongs to the 5'-nucleotidase family.	Uridine kinase.	0.920
ABC2847	ABC0966	ABC2847	ABC0966	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	Nucleotidase; Belongs to the 5'-nucleotidase family.	0.903
ABC2847	comEB	ABC2847	ABC1647	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	Late competence protein ComEB.	0.937
ABC2847	tdk	ABC2847	ABC3877	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	Thymidine kinase.	0.958
ABC2847	thyB	ABC2847	ABC2955	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.	0.957
ABC2847	tmk	ABC2847	ABC0050	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.	0.955