node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABC1472 | ABC1946 | ABC1472 | ABC1946 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.913 |
ABC1472 | ABC3912 | ABC1472 | ABC3912 | Conserved hypothetical protein. | Conserved hypothetical protein; May function as heme-dependent peroxidase. | 0.917 |
ABC1472 | ctaB | ABC1472 | ABC2902 | Conserved hypothetical protein. | Cytochrome oxidase assembly factor; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily. | 0.900 |
ABC1472 | hemH | ABC1472 | ABC1539 | Conserved hypothetical protein. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.911 |
ABC1472 | isdG | ABC1472 | ABC3425 | Conserved hypothetical protein. | Conserved hypothetical protein; Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the biliverdin in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron; Belongs to the antibiotic biosynthesis monooxygenase family. Heme-degrading monooxygenase IsdG subfamily. | 0.913 |
ABC1946 | ABC1472 | ABC1946 | ABC1472 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.913 |
ABC1946 | ABC3912 | ABC1946 | ABC3912 | Conserved hypothetical protein. | Conserved hypothetical protein; May function as heme-dependent peroxidase. | 0.904 |
ABC1946 | ctaB | ABC1946 | ABC2902 | Conserved hypothetical protein. | Cytochrome oxidase assembly factor; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily. | 0.900 |
ABC1946 | hemH | ABC1946 | ABC1539 | Conserved hypothetical protein. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.904 |
ABC1946 | isdG | ABC1946 | ABC3425 | Conserved hypothetical protein. | Conserved hypothetical protein; Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the biliverdin in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron; Belongs to the antibiotic biosynthesis monooxygenase family. Heme-degrading monooxygenase IsdG subfamily. | 0.937 |
ABC2189 | ABC3902 | ABC2189 | ABC3902 | Conserved hypothetical protein; Belongs to the UPF0342 family. | Conserved hypothetical protein. | 0.767 |
ABC2189 | ABC3912 | ABC2189 | ABC3912 | Conserved hypothetical protein; Belongs to the UPF0342 family. | Conserved hypothetical protein; May function as heme-dependent peroxidase. | 0.493 |
ABC2901 | ABC3902 | ABC2901 | ABC3902 | Cytochrome c biogenesis protein. | Conserved hypothetical protein. | 0.507 |
ABC2901 | ABC3912 | ABC2901 | ABC3912 | Cytochrome c biogenesis protein. | Conserved hypothetical protein; May function as heme-dependent peroxidase. | 0.566 |
ABC2901 | ctaB | ABC2901 | ABC2902 | Cytochrome c biogenesis protein. | Cytochrome oxidase assembly factor; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily. | 0.687 |
ABC3902 | ABC2189 | ABC3902 | ABC2189 | Conserved hypothetical protein. | Conserved hypothetical protein; Belongs to the UPF0342 family. | 0.767 |
ABC3902 | ABC2901 | ABC3902 | ABC2901 | Conserved hypothetical protein. | Cytochrome c biogenesis protein. | 0.507 |
ABC3902 | ABC3912 | ABC3902 | ABC3912 | Conserved hypothetical protein. | Conserved hypothetical protein; May function as heme-dependent peroxidase. | 0.538 |
ABC3911 | ABC3912 | ABC3911 | ABC3912 | enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | Conserved hypothetical protein; May function as heme-dependent peroxidase. | 0.522 |
ABC3912 | ABC1472 | ABC3912 | ABC1472 | Conserved hypothetical protein; May function as heme-dependent peroxidase. | Conserved hypothetical protein. | 0.917 |