| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABC1075 | apt | ABC1075 | ABC1569 | Adenine deaminase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.914 |
| ABC1075 | deoD | ABC1075 | ABC4021 | Adenine deaminase. | Purine-nucleoside phosphorylase. | 0.905 |
| ABC1075 | hprT | ABC1075 | ABC0105 | Adenine deaminase. | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.919 |
| ABC1075 | pupG | ABC1075 | ABC3722 | Adenine deaminase. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.902 |
| ABC1075 | xpt | ABC1075 | ABC1443 | Adenine deaminase. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.530 |
| ABC3966 | deoD | ABC3966 | ABC4021 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Purine-nucleoside phosphorylase. | 0.948 |
| ABC3966 | pupG | ABC3966 | ABC3722 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.914 |
| apt | ABC1075 | ABC1569 | ABC1075 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenine deaminase. | 0.914 |
| apt | deoD | ABC1569 | ABC4021 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Purine-nucleoside phosphorylase. | 0.917 |
| apt | hprT | ABC1569 | ABC0105 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.545 |
| apt | pupG | ABC1569 | ABC3722 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.929 |
| apt | xpt | ABC1569 | ABC1443 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.478 |
| cobB | deoD | ABC0638 | ABC4021 | Sir2 family transcriptional regulator; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | Purine-nucleoside phosphorylase. | 0.955 |
| cobB | pupG | ABC0638 | ABC3722 | Sir2 family transcriptional regulator; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.914 |
| dck | deoD | ABC2890 | ABC4021 | Deoxypurine kinase. | Purine-nucleoside phosphorylase. | 0.906 |
| dck | dgk | ABC2890 | ABC2889 | Deoxypurine kinase. | Deoxypurine kinase. | 0.908 |
| dck | pupG | ABC2890 | ABC3722 | Deoxypurine kinase. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.902 |
| deoD | ABC1075 | ABC4021 | ABC1075 | Purine-nucleoside phosphorylase. | Adenine deaminase. | 0.905 |
| deoD | ABC3966 | ABC4021 | ABC3966 | Purine-nucleoside phosphorylase. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.948 |
| deoD | apt | ABC4021 | ABC1569 | Purine-nucleoside phosphorylase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.917 |