| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABC2769 | dnaA | ABC2769 | ABC0001 | DNA translocase; Belongs to the FtsK/SpoIIIE/SftA family. | Chromosome replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.553 |
| ABC2769 | noc | ABC2769 | ABC4114 | DNA translocase; Belongs to the FtsK/SpoIIIE/SftA family. | Transcriptional regulator; Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage. Belongs to the ParB family. | 0.762 |
| ABC2769 | ribA | ABC2769 | ABC1812 | DNA translocase; Belongs to the FtsK/SpoIIIE/SftA family. | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | 0.467 |
| ABC2769 | soj | ABC2769 | ABC4113 | DNA translocase; Belongs to the FtsK/SpoIIIE/SftA family. | Sporulation initiation inhibitor protein Soj. | 0.728 |
| ABC2769 | spo0J | ABC2769 | ABC4112 | DNA translocase; Belongs to the FtsK/SpoIIIE/SftA family. | Stage 0 sporulation protein J; Antagonist of Soj; Belongs to the ParB family. | 0.786 |
| ABC4111 | noc | ABC4111 | ABC4114 | Selenocysteine lyase. | Transcriptional regulator; Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage. Belongs to the ParB family. | 0.472 |
| ABC4111 | soj | ABC4111 | ABC4113 | Selenocysteine lyase. | Sporulation initiation inhibitor protein Soj. | 0.683 |
| ABC4111 | spo0J | ABC4111 | ABC4112 | Selenocysteine lyase. | Stage 0 sporulation protein J; Antagonist of Soj; Belongs to the ParB family. | 0.690 |
| birA | dnaA | ABC2068 | ABC0001 | Bifunctional biotin biosynthesis protein BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Chromosome replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.411 |
| birA | ribA | ABC2068 | ABC1812 | Bifunctional biotin biosynthesis protein BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | 0.752 |
| birA | soj | ABC2068 | ABC4113 | Bifunctional biotin biosynthesis protein BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Sporulation initiation inhibitor protein Soj. | 0.750 |
| dnaA | ABC2769 | ABC0001 | ABC2769 | Chromosome replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA translocase; Belongs to the FtsK/SpoIIIE/SftA family. | 0.553 |
| dnaA | birA | ABC0001 | ABC2068 | Chromosome replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Bifunctional biotin biosynthesis protein BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.411 |
| dnaA | ftsZ | ABC0001 | ABC2353 | Chromosome replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Cell division initiation protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.404 |
| dnaA | gidB | ABC0001 | ABC4115 | Chromosome replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Glucose inhibited division protein B; Specifically methylates the N7 position of guanine in position 535 of 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | 0.425 |
| dnaA | noc | ABC0001 | ABC4114 | Chromosome replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Transcriptional regulator; Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage. Belongs to the ParB family. | 0.521 |
| dnaA | soj | ABC0001 | ABC4113 | Chromosome replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Sporulation initiation inhibitor protein Soj. | 0.803 |
| dnaA | spo0J | ABC0001 | ABC4112 | Chromosome replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Stage 0 sporulation protein J; Antagonist of Soj; Belongs to the ParB family. | 0.606 |
| dnaA | spoIIIE | ABC0001 | ABC2210 | Chromosome replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA translocase stage III sporulation protein E; Belongs to the FtsK/SpoIIIE/SftA family. | 0.550 |
| ftsZ | dnaA | ABC2353 | ABC0001 | Cell division initiation protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Chromosome replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.404 |