STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
moaCMolybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (158 aa)    
Predicted Functional Partners:
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
 0.999
AEH45388.1
Molybdenum cofactor synthesis domain protein; COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR020817:IPR008284:IPR001453; KEGG: pca:Pcar_1966 molybdenum cofactor biosynthesis protein; PFAM: molybdopterin binding domain; SPTR: Molybdenum cofactor biosynthesis protein; TIGRFAM: molybdenum cofactor synthesis domain protein; IMG reference gene:2505284846; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain.
  
 0.994
AEH46059.1
MoaD family protein; InterPro IPR003749:IPR010038; KEGG: pmo:Pmob_0384 MoaD family protein; PFAM: thiamineS protein; SPTR: MoaD family protein; TIGRFAM: MoaD family protein; IMG reference gene:2505285550; PFAM: ThiS family; TIGRFAM: MoaD family protein, archaeal.
  
  
 0.937
AEH45561.1
Molybdopterin biosynthesis MoaE protein; InterPro IPR003448; KEGG: tye:THEYE_A0839 molybdopterin converting factor, subunit 2; PFAM: molybdopterin biosynthesis MoaE protein; SPTR: Protein involved in biosynthesis of molybdopterin; IMG reference gene:2505285026; PFAM: MoaE protein.
  
  
 0.901
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
       0.818
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
       0.818
AEH44763.1
Radical SAM domain protein; COGs: COG2896 Molybdenum cofactor biosynthesis protein; InterPro IPR007197:IPR006638:IPR000385; KEGG: afu:AF2104 hypothetical protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative uncharacterized protein; IMG reference gene:2505284190; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM additional 4Fe4S-binding domain.
  
  
 0.801
AEH45727.1
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
  
 0.801
dksA
Transcriptional regulator, TraR/DksA family; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.
       0.794
AEH45708.1
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
  
 0.792
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.