Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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AEH43898.1Glycoside hydrolase family 57; COGs: COG1449 Alpha-amylase/alpha-mannosidase; InterPro IPR004300; KEGG: nde:NIDE3392 glycoside hydrolase family 57 protein; PFAM: glycoside hydrolase family 57; SPTR: Glycoside hydrolase, family 57; IMG reference gene:2505283293; PFAM: Glycosyl hydrolase family 57. (708 aa)    
Predicted Functional Partners:
AEH43899.1
COGs: COG1085 Galactose-1-phosphate uridylyltransferase; InterPro IPR005850:IPR001937; KEGG: dak:DaAHT2_1705 galactose-1-phosphate uridylyltransferase; PFAM: galactose-1-phosphate uridyl transferase domain protein; PRIAM: UDP-glucose--hexose-1-phosphate uridylyltransferase; SPTR: Galactose-1-phosphate uridylyltransferase; TIGRFAM: galactose-1-phosphate uridylyltransferase; IMG reference gene:2505283294; PFAM: Galactose-1-phosphate uridyl transferase, C-terminal domain; Galactose-1-phosphate uridyl transferase, N-terminal domain; TIGRFAM: galactose-1-phosphate uridylyltransferase, family 1.
 
     0.872
dksA
Transcriptional regulator, TraR/DksA family; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.
       0.778
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
       0.757
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
       0.757
moaC
Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
       0.757
AEH43900.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dak:DaAHT2_1706 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; IMG reference gene:2505283295; PFAM: Response regulator receiver domain.
       0.732
AEH43893.1
COGs: COG0694 Thioredoxin-like protein and domains; InterPro IPR001075; KEGG: drt:Dret_1408 nitrogen-fixing NifU domain protein; PFAM: nitrogen-fixing NifU domain protein; SPTR: Nitrogen-fixing NifU domain protein; IMG reference gene:2505283288; PFAM: NifU-like domain.
       0.726
AEH44668.1
4-alpha-glucanotransferase; COGs: COG1449 Alpha-amylase/alpha-mannosidase; InterPro IPR015178:IPR004300:IPR015179; KEGG: tsi:TSIB_0455 4-alpha-glucanotransferase; PFAM: glycoside hydrolase family 57; Domain of unknown function DUF1925; Domain of unknown function DUF1926; PRIAM: 4-alpha-glucanotransferase; SPTR: Cyclodextrin glucanotransferase; IMG reference gene:2505284087; PFAM: Domain of unknown function (DUF1925); Glycosyl hydrolase family 57; Domain of unknown function (DUF1926).
  
     0.640
AEH45895.1
Glycoside hydrolase family 57; COGs: COG1543 conserved hypothetical protein; InterPro IPR004300; KEGG: pth:PTH_2228 hypothetical protein; PFAM: glycoside hydrolase family 57; SPTR: Uncharacterized conserved protein; IMG reference gene:2505285382; PFAM: Domain of unknown function (DUF1957); Glycosyl hydrolase family 57.
 
   
 0.587
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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