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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH43902.1Sigma54 specific transcriptional regulator, Fis family; COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterPro IPR020441:IPR002078:IPR002197:IPR003593; KEGG: acp:A2cp1_2835 two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; SPTR: Two component, sigma54 specific, transcriptional regulator, Fis family; IMG reference gene:2505283297; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain. (350 aa)    
Predicted Functional Partners:
AEH43901.1
NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: chy:CHY_1057 hypothetical protein; PFAM: NAD-dependent epimerase/dehydratase; SPTR: Conserved domain protein; IMG reference gene:2505283296; PFAM: NAD dependent epimerase/dehydratase family.
       0.779
AEH45268.1
COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394:IPR007046:IPR007634; KEGG: sat:SYN_00945 RNA polymerase sigma-54 factor; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; SPTR: RNA polymerase sigma-54 factor; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; IMG reference gene:2505284717; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54, DNA binding domain; Sigma-54 factor, core binding domain; TIGRFAM: RNA polymerase sigma-54 factor.
  
   
 0.763
AEH43903.1
Inosine guanosine and xanthosine phosphorylase family; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
       0.554
AEH43904.1
Ribonuclease, Rne/Rng family; COGs: COG1530 Ribonuclease G and E; InterPro IPR003029:IPR019307:IPR004659:IPR018247; KEGG: gsu:GSU3239 ribonuclease G; PFAM: RNA-binding protein AU-1/Ribonuclease E/G; RNA binding S1 domain protein; SPTR: Ribonuclease G; TIGRFAM: ribonuclease, Rne/Rng family; IMG reference gene:2505283299; PFAM: Ribonuclease E/G family; S1 RNA binding domain; TIGRFAM: ribonuclease, Rne/Rng family.
       0.554
AEH44973.1
COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterProIPR003661:IPR003594:IPR001789:IPR004358:IPR 000014:IPR005467; KEGG: ddf:DEFDS_0784 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SPTR: Putative uncharacterized protein; TIGRFAM: PAS sensor protein; IMG reference gene:2505284412; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator re [...]
  
 
 0.514
AEH44230.1
CheA signal transduction histidine kinase; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207:IPR004105:IPR003594:IPR002545:IPR 001789:IPR004358:IPR005467; KEGG: dps:DP2642 Che family two-component system sensory/regulatory protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; CheW domain protein; SMART: response regulator receiver; CheW domain protein; ATP-binding region ATPase domain protein; Hpt domain protein; SPTR: Two-component system sensory/r [...]
  
 
 0.486
AEH44065.1
COGs: COG1868 Flagellar motor switch protein; InterPro IPR001689:IPR001543; KEGG: sat:SYN_02837 flagellar motor switch protein; PFAM: flagellar motor switch protein FliM; surface presentation of antigens (SPOA) protein; SPTR: Flagellar motor switch protein; TIGRFAM: flagellar motor switch protein FliM; IMG reference gene:2505283463; PFAM: Surface presentation of antigens (SPOA); Flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM.
   
  
 0.401
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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