Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH43930.11-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; COGs: COG1691 NCAIR mutase (PurE)-related protein; InterPro IPR000031; KEGG: dal:Dalk_0112 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; SPTR: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; IMG reference gene:2505283327; PFAM: AIR carboxylase. (255 aa)    
Predicted Functional Partners:
AEH45221.1
Asparagine synthase; COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; InterPro IPR005232:IPR001962; KEGG: ate:Athe_1202 PP-loop domain protein; PFAM: asparagine synthase; SPTR: PP-loop domain protein; IMG reference gene:2505284668; PFAM: Asparagine synthase; TIGRFAM: TIGR00268 family protein.
 
 
 0.965
AEH44543.1
Protein of unknown function DUF111; COGs: COG1641 conserved hypothetical protein; InterPro IPR002822; KEGG: dth:DICTH_1434 hypothetical protein; PFAM: protein of unknown function DUF111; SPTR: UPF0272 protein DICTH_1434; IMG reference gene:2505283959; PFAM: Protein of unknown function DUF111; TIGRFAM: TIGR00299 family protein; Belongs to the LarC family.
 
  
 0.915
AEH43931.1
KEGG: pth:PTH_1373 serine protease inhibitor; SPTR: Putative uncharacterized protein; IMG reference gene:2505283328.
       0.782
AEH43929.1
Nucleoside recognition domain protein; COGs: COG2715 Uncharacterized membrane protein required for spore maturation in B.subtilis; InterPro IPR011642:IPR011415; KEGG: ter:Tery_2909 nucleoside recognition; PFAM: nucleoside recognition domain protein; SPTR: Nucleoside recognition; IMG reference gene:2505283326; PFAM: Nucleoside recognition.
       0.778
AEH44880.1
Cobalamin (vitamin B12) biosynthesis CbiM protein; COGs: COG0310 ABC-type Co2+ transport system permease component; InterPro IPR002751; KEGG: dsa:Desal_0774 cobalt transport protein CbiM; PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; SPTR: Cobalamin (Vitamin B12) biosynthesis CbiM protein; IMG reference gene:2505284318; PFAM: Cobalt uptake substrate-specific transmembrane region; TIGRFAM: cobalamin biosynthesis protein CbiM.
  
    0.646
AEH43932.1
COGs: COG0212 5-formyltetrahydrofolate cyclo-ligase; InterPro IPR002698; KEGG: cbe:Cbei_0291 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; SPTR: 5-formyltetrahydrofolate cyclo-ligase; TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; IMG reference gene:2505283329; PFAM: 5-formyltetrahydrofolate cyclo-ligase family; TIGRFAM: 5,10-methenyltetrahydrofolate synthetase.
       0.541
AEH43928.1
COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR001176:IPR004839:IPR005958:IPR004838; KEGG: aba:Acid345_1458 aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aminotransferase; TIGRFAM: tyrosine/nicotianamine aminotransferase; IMG reference gene:2505283325; PFAM: Aminotransferase class I and II; TIGRFAM: tyrosine aminotransferase, eukaryotic; tyrosine/nicotianamine aminotransferases.
       0.458
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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