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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH43950.1COGs: COG1785 Alkaline phosphatase; InterPro IPR001952; KEGG: pca:Pcar_0512 alkaline phosphatase; PFAM: Alkaline phosphatase; PRIAM: Alkaline phosphatase; SMART: Alkaline phosphatase; SPTR: Alkaline phosphatase; IMG reference gene:2505283347; PFAM: Alkaline phosphatase; Belongs to the alkaline phosphatase family. (504 aa)    
Predicted Functional Partners:
AEH45618.1
COGs: COG1785 Alkaline phosphatase; InterPro IPR001952; KEGG: dsa:Desal_1742 alkaline phosphatase; PFAM: Alkaline phosphatase; SMART: Alkaline phosphatase; SPTR: Alkaline phosphatase; IMG reference gene:2505285087; PFAM: Alkaline phosphatase; Belongs to the alkaline phosphatase family.
  
  
 
0.928
AEH44406.1
Phosphomethylpyrimidine kinase; COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR004399:IPR013749:IPR019293; KEGG: pho:PH1155 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; Phosphomethylpyrimidine kinase; PRIAM: Phosphomethylpyrimidine kinase; SPTR: 446aa long hypothetical thiamine biosynthesis protein; TIGRFAM: phosphomethylpyrimidine kinase; IMG reference gene:2505283818; PFAM: Phosphomethylpyrimidine kinase; Archaeal phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase.
    
 0.903
folE2
GTP cyclohydrolase I; Converts GTP to 7,8-dihydroneopterin triphosphate.
     
  0.900
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
     
  0.900
AEH44773.1
COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: sfu:Sfum_0003 putative 6-pyruvoyl tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284200; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein.
     
  0.900
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
     
  0.900
AEH43951.1
Protein of unknown function DUF1555; InterPro IPR011449:IPR013424; KEGG: cps:CPS_0379 hypothetical protein; PFAM: protein of unknown function DUF1555; SPTR: Putative uncharacterized protein; IMG reference gene:2505283348; TIGRFAM: PEP-CTERM putative exosortase interaction domain.
       0.714
secA
Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.
    
 
 0.614
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
    
 
 0.592
AEH45619.1
YibE/F family protein; COGs: COG5438 multitransmembrane protein; InterPro IPR012507; KEGG: dsa:Desal_1743 YibE/F family protein; PFAM: YibE/F family protein; SPTR: YibE/F family protein; IMG reference gene:2505285088; PFAM: YibE/F-like protein.
 
     0.569
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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