Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH43954.1ParB domain protein nuclease; InterPro IPR003115; KEGG: dol:Dole_2368 nuclease; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: ParB domain protein nuclease; IMG reference gene:2505283351; PFAM: ParB-like nuclease domain. (310 aa)    
Predicted Functional Partners:
AEH43956.1
KEGG: dal:Dalk_0401 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505283353; PFAM: Rho termination factor, N-terminal domain.
 
     0.831
purC
COGs: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; InterPro IPR001636:IPR018236; KEGG: dol:Dole_2369 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; PRIAM: Phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: Phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; IMG reference gene:2505283352; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase.
  
    0.787
AEH44979.1
COGs: COG1533 DNA repair photolyase; KEGG: dal:Dalk_0910 DNA repair photolyase-like protein; SPTR: DNA repair photolyase-like protein; IMG reference gene:2505284418.
 
     0.650
AEH44519.1
ParA protein; COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: bgl:bglu_1g17180 ParA protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505283934; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
  
 
 0.648
AEH44850.1
Cobyrinic acid a,c-diamide synthase; COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: ppd:Ppro_0583 cobyrinic acid a,c-diamide synthase; SPTR: Chromosome segregation ATPase; IMG reference gene:2505284287; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
  
 
 0.648
AEH44459.1
KEGG: dal:Dalk_3199 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505283872.
  
     0.606
AEH43957.1
KEGG: afm:AFUA_7G05520 hypothetical protein; SPTR: Two component transcriptional regulator, AraC family; IMG reference gene:2505283354.
       0.550
AEH44804.1
KEGG: dal:Dalk_0095 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284237.
  
     0.519
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.504
rsmG
Glucose inhibited division protein; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
  
  
 0.492
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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