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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (449 aa)    
Predicted Functional Partners:
glmS
Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
 
 
 0.939
AEH45203.1
COGs: COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); InterPro IPR005835; KEGG: dae:Dtox_0205 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; PFAM: Nucleotidyl transferase; PRIAM: Glucosamine-1-phosphate N-acetyltransferase; SPTR: Bifunctional protein glmU; IMG reference gene:2505284650; PFAM: Nucleotidyl transferase; TIGRFAM: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase.
 
 0.920
dacA
Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
   
 
 0.875
AEH43962.1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
  
  
 0.804
ftsH
ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
  
 0.794
AEH43960.1
YbbR family protein; COGs: COG4856 conserved hypothetical protein; InterPro IPR012505; KEGG: ddf:DEFDS_1032 hypothetical protein; PFAM: YbbR family protein; SPTR: YbbR-like; IMG reference gene:2505283357; PFAM: YbbR-like protein.
  
  
 0.767
AEH44764.1
Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR005835:IPR001538:IPR006375; KEGG: saf:SULAZ_0358 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; PRIAM: Mannose-6-phosphate isomerase; SPTR: Strongly similar to GDP-mannose pyrophosphorylase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; IMG reference gene:2505284191; PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomera [...]
  
  
 0.655
AEH44593.1
Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362:IPR017472:IPR017475; KEGG: hya:HY04AAS1_0831 undecaprenyl-phosphate galactose phosphotransferase, WbaP; PFAM: sugar transferase; PRIAM: Undecaprenyl-phosphate galactose phosphotransferase; SPTR: Undecaprenyl-phosphate galactosephosphotransferase; TIGRFAM: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Undecaprenyl-phosphate galactose phosphotransferase, WbaP; IMG reference gene:2505284010; PFAM: Bacteri [...]
  
  
 0.639
AEH44898.1
Protein of unknown function DUF147; COGs: COG1624 conserved hypothetical protein; InterPro IPR003390; KEGG: caa:Caka_1512 protein of unknown function DUF147; PFAM: protein of unknown function DUF147; SPTR: Putative uncharacterized protein; IMG reference gene:2505284337; PFAM: DisA bacterial checkpoint controller nucleotide-binding.
   
 
 0.528
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.501
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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