Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEH43980.1Indolepyruvate ferredoxin oxidoreductase, alpha subunit; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (564 aa)    
Predicted Functional Partners:
AEH43979.1
COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR019752; KEGG: dal:Dalk_5038 indolepyruvate ferredoxin oxidoreductase; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; PRIAM: Indolepyruvate ferredoxin oxidoreductase; SPTR: Indolepyruvate ferredoxin oxidoreductase; IMG reference gene:2505283376; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: indolepyruvate ferredoxin oxidoreductase, beta subunit.
 
 
 0.961
AEH46025.1
Formate dehydrogenase, alpha subunit; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR000759:IPR001041:IPR013027:IPR006963:IPR 006656:IPR006657:IPR018247:IPR017900:IPR006655:IPR017896:I PR006478; KEGG: dak:DaAHT2_0823 formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; ferredoxin; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; SPTR: Formate dehydrogenase, alpha subunit; TIGRFAM: formate dehydrogenase, alpha subunit; manually curated; selenocysteine- [...]
   
 
 0.945
AEH46031.1
COGs: COG1614 CO dehydrogenase/acetyl-CoA synthase beta subunit; InterPro IPR004461; KEGG: dak:DaAHT2_0825 CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase complex beta subunit; PRIAM: CO-methylating acetyl-CoA synthase; SPTR: CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; TIGRFAM: CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; IMG reference gene:2505285520; PFAM: CO dehydrogenase/acetyl-CoA synthase complex beta subunit; TIGRFAM: CO dehydrogenase/CO-methylating acetyl-CoA synthase complex, beta subunit.
    
   0.847
AEH44377.1
Hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR013352:IPR004108:IPR003149:IPR017896:IPR 017900; KEGG: hor:Hore_06330 NADH dehydrogenase (ubiquinone) 75 kDa subunit; PFAM: hydrogenase large subunit domain protein; iron hydrogenase small subunit; PRIAM: Ferredoxin hydrogenase; SPTR: NADH dehydrogenase (Ubiquinone) 75 kDa subunit; TIGRFAM: hydrogenase, Fe-only; IMG reference gene:2505283784; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Iron hydrogenase small subunit; TIGRFAM: hydrogenase, Fe-only.
   
 
 0.620
AEH43981.1
Hypothetical protein; KEGG: sfr:Sfri_1790 Fmu (Sun) domain-containing protein; SPTR: Fmu (Sun) domain protein; IMG reference gene:2505283378.
       0.586
AEH44040.1
COGs: COG4747 ACT domain-containing protein; InterPro IPR002912; KEGG: slp:Slip_0779 amino acid-binding ACT domain protein; PFAM: amino acid-binding ACT domain protein; SPTR: Amino acid-binding ACT domain protein; IMG reference gene:2505283438; PFAM: ACT domain.
 
    0.583
AEH45676.1
Nitrate reductase; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterProIPR006311:IPR017909:IPR006655:IPR006963:IPR 006656:IPR006657; KEGG: ddf:DEFDS_1331 formate dehydrogenase subunit alpha; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; PRIAM: Nitrate reductase; SPTR: Formate dehydrogenase, alpha subunit; manually curated; selenocysteine-containing protein; IMG reference gene:2505285147; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxi [...]
   
 
 0.512
AEH44169.1
Adenylylsulfate reductase, alpha subunit; COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953:IPR011803; KEGG: drt:Dret_1966 adenylylsulfate reductase subunit alpha; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: AprA; TIGRFAM: adenylylsulfate reductase, alpha subunit; IMG reference gene:2505283574; PFAM: domain; FAD binding domain; TIGRFAM: adenosine phosphosulphate reductase, alpha subunit.
  
 
 0.468
AEH44039.1
Phenylacetate--CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).
 
    0.448
AEH46061.1
Phenylacetate--CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).
 
    0.446
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: low (26%) [HD]