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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH43983.1Ferric uptake regulator, Fur family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: sat:SYN_02524 ferric uptake regulator family protein; PFAM: ferric-uptake regulator; SPTR: Ferric uptake regulator family protein; IMG reference gene:2505283380; PFAM: Ferric uptake regulator family; Belongs to the Fur family. (138 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.586
AEH44835.1
Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; COGs: COG0450 Peroxiredoxin; InterPro IPR000866:IPR019479:IPR017936; KEGG: dae:Dtox_2806 peroxiredoxin; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Peroxiredoxin-like; SPTR: Peroxiredoxin; manually curated; selenocysteine-containing protein; IMG reference gene:2505284269; PFAM: C-terminal domain of 1-Cys peroxiredoxin; AhpC/TSA family.
  
  
 0.577
AEH43981.1
Hypothetical protein; KEGG: sfr:Sfri_1790 Fmu (Sun) domain-containing protein; SPTR: Fmu (Sun) domain protein; IMG reference gene:2505283378.
       0.505
AEH45588.1
COGs: COG1832 CoA-binding protein; InterPro IPR003781; KEGG: mta:Moth_2421 CoA-binding; PFAM: CoA-binding domain protein; SPTR: CoA-binding; IMG reference gene:2505285055; PFAM: CoA binding domain.
  
    0.505
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.492
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.491
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.489
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
   0.483
AEH44399.1
COGs: COG0681 Signal peptidase I; InterProIPR000223:IPR019759:IPR019756:IPR019757:IPR 019758; KEGG: tye:THEYE_A0098 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; PRIAM: Signal peptidase I; SPTR: Signal peptidase I; TIGRFAM: signal peptidase I; IMG reference gene:2505283811; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type.
   
    0.439
sigA
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.430
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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