Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEH43989.1COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017:IPR017896:IPR017900; KEGG: drt:Dret_1037 protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505283386; PFAM: Cysteine-rich domain. (334 aa)    
Predicted Functional Partners:
AEH45876.1
FAD linked oxidase domain protein; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113:IPR016166; KEGG: tye:THEYE_A0668 glycolate oxidase subunit; PFAM: FAD linked oxidase domain protein; SPTR: Glycolate oxidase subunit; IMG reference gene:2505285362; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD.
 
 
 0.966
AEH43888.1
FAD linked oxidase domain protein; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113:IPR016166:IPR020904; KEGG: sfu:Sfum_0534 FAD linked oxidase domain-containing protein; PFAM: FAD linked oxidase domain protein; SPTR: FAD linked oxidase domain protein; manually curated; IMG reference gene:2505283283; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD.
 
 
 0.962
AEH45875.1
CoB--CoM heterodisulfide reductase; COGs: COG0247 Fe-S oxidoreductase; InterPro IPR012257:IPR017900:IPR004017:IPR017896; KEGG: tye:THEYE_A0667 iron-sulfur cluster-binding protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; PRIAM: CoB--CoM heterodisulfide reductase; SPTR: Iron-sulfur cluster-binding protein; IMG reference gene:2505285361; PFAM: Cysteine-rich domain.
  
  
 
0.927
AEH44441.1
Haloacid dehalogenase domain protein hydrolase; COGs: COG0546 phosphatase; InterPro IPR005834:IPR005833; KEGG: dak:DaAHT2_2039 HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: HAD-superfamily hydrolase, subfamily IA, variant 3; IMG reference gene:2505283854; PFAM: haloacid dehalogenase-like hydrolase.
    
 0.902
AEH43990.1
Metal dependent phosphohydrolase; COGs: COG1896 hydrolase of HD superfamily; InterPro IPR006674:IPR003607; KEGG: sfu:Sfum_3021 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal dependent phosphohydrolase; IMG reference gene:2505283387; PFAM: HD domain.
       0.789
AEH43988.1
COGs: COG1416 conserved hypothetical protein; KEGG: dsa:Desal_3394 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505283385; PFAM: DsrE/DsrF-like family.
       0.563
AEH44959.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR002355:IPR001763:IPR013027:IPR004099; KEGG: dps:DP2890 NADH oxidase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SMART: Rhodanese domain protein; SPTR: Related to NADH oxidase; IMG reference gene:2505284398; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Rhodanese-like domain; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.
  
  
 0.480
AEH43987.1
ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
   
   0.452
AEH43991.1
ADP-ribosylation/Crystallin J1; COGs: COG1397 ADP-ribosylglycohydrolase; InterPro IPR005502; KEGG: mrb:Mrub_0165 ADP-ribosylation/crystallin J1; PFAM: ADP-ribosylation/Crystallin J1; SPTR: ADP-ribosylation/Crystallin J1; IMG reference gene:2505283388; PFAM: ADP-ribosylglycohydrolase; TIGRFAM: ADP-ribosyl-[dinitrogen reductase] hydrolase.
       0.437
AEH46025.1
Formate dehydrogenase, alpha subunit; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR000759:IPR001041:IPR013027:IPR006963:IPR 006656:IPR006657:IPR018247:IPR017900:IPR006655:IPR017896:I PR006478; KEGG: dak:DaAHT2_0823 formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; ferredoxin; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; SPTR: Formate dehydrogenase, alpha subunit; TIGRFAM: formate dehydrogenase, alpha subunit; manually curated; selenocysteine- [...]
 
   
 0.400
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.