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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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[Homology]
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AEH44002.1Peptidase M22 glycoprotease; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905; KEGG: dak:DaAHT2_0975 peptidase M22 glycoprotease; PFAM: peptidase M22 glycoprotease; SPTR: Peptidase M22 glycoprotease; IMG reference gene:2505283399; PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ. (240 aa)    
Predicted Functional Partners:
AEH45691.1
Uncharacterized protein family UPF0079, ATPase; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: lsa:LSA1342 hypothetical protein; PFAM: Uncharacterised protein family UPF0079, ATPase; SPTR: Putative uncharacterized protein; IMG reference gene:2505285162; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family.
 
 
 0.979
tsaD
Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
 
 0.979
AEH45273.1
Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.
  
 0.921
AEH44004.1
COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: sat:SYN_01342 oligopeptide transport system permease protein; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Oligopeptide transport system permease protein; IMG reference gene:2505283401; PFAM: Binding-protein-dependent transport system inner membrane component.
  
    0.782
AEH44003.1
COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: gme:Gmet_1235 binding-protein dependent transport system inner membrane protein; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; IMG reference gene:2505283400; PFAM: Binding-protein-dependent transport system inner membrane component.
       0.780
AEH45631.1
HAD-superfamily hydrolase, subfamily IA, variant 3; COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR005833:IPR006402:IPR006439:IPR005834; KEGG: rsd:TGRD_051 putative phosphatase/phosphohexomutase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Putative phosphatase/phosphohexomutase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; IMG reference gene:2505285101; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED.
      0.682
AEH43923.1
Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
    
 0.681
AEH44917.1
Phage SPO1 DNA polymerase-related protein; COGs: COG1573 Uracil-DNA glycosylase; InterPro IPR005122:IPR005273; KEGG: rpf:Rpic12D_1308 phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily; SPTR: Putative uncharacterized protein; TIGRFAM: phage SPO1 DNA polymerase-related protein; IMG reference gene:2505284356; PFAM: Uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase family domain; uracil-DNA glycosylase, family 4.
  
    0.591
AEH44001.1
Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR001808:IPR000595:IPR012318; KEGG: dal:Dalk_2705 transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; SPTR: Transcriptional regulator, Crp/Fnr family; IMG reference gene:2505283398; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain.
  
    0.577
AEH44005.1
Heat shock protein Hsp20; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: tna:CTN_0305 heat shock protein HSP20; PFAM: heat shock protein Hsp20; SPTR: Putative HspC2 heat shock protein; IMG reference gene:2505283402; PFAM: Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family.
       0.570
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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