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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44011.1CDP-alcohol phosphatidyltransferase; COGs: COG1213 sugar nucleotidyltransferase; InterPro IPR005835:IPR000462; KEGG: aae:aq_1367 glucose-1-phosphate thymidylyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Nucleotidyl transferase; SPTR: Glucose-1-phosphate thymidylyltransferase; IMG reference gene:2505283409; PFAM: Nucleotidyl transferase; CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (430 aa)    
Predicted Functional Partners:
AEH44632.1
COGs: COG1260 Myo-inositol-1-phosphate synthase; InterPro IPR002587:IPR013021; KEGG: aae:aq_1763 hypothetical protein; PFAM: Myo-inositol-1-phosphate synthase; Myo-inositol-1-phosphate synthase GAPDH domain protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284051; PFAM: Myo-inositol-1-phosphate synthase.
 
  
 0.946
AEH45185.1
Inositol monophosphatase; COGs: COG0483 fructose-1 6-bisphosphatase of inositol monophosphatase family; InterPro IPR000760:IPR020583:IPR020550; KEGG: dak:DaAHT2_0139 inositol monophosphatase; PFAM: inositol monophosphatase; SPTR: Inositol monophosphatase; IMG reference gene:2505284632; PFAM: Inositol monophosphatase family.
  
 
 0.918
AEH44861.1
Competence/damage-inducible protein CinA; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR001453:IPR008136:IPR008135; KEGG: dps:DP2957 competence-damage inducible protein (CinA); PFAM: CinA domain protein; molybdopterin binding domain; SPTR: CinA-like protein; TIGRFAM: competence/damage-inducible protein CinA; IMG reference gene:2505284298; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybden [...]
  
  
 0.785
AEH44010.1
Periplasmic solute binding protein; COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; InterPro IPR006129:IPR006128:IPR006127; KEGG: gme:Gmet_0491 periplasmic solute binding protein; PFAM: periplasmic solute binding protein; SPTR: Periplasmic solute binding protein; IMG reference gene:2505283408; PFAM: Periplasmic solute binding protein family; Belongs to the bacterial solute-binding protein 9 family.
       0.644
AEH44012.1
RimK domain protein ATP-grasp; COGs: COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); InterPro IPR013651:IPR011761; KEGG: dak:DaAHT2_2245 RimK domain protein ATP-grasp; PFAM: RimK domain protein ATP-grasp; SPTR: RimK domain protein ATP-grasp; IMG reference gene:2505283410; PFAM: RimK-like ATP-grasp domain.
       0.641
AEH44340.1
COGs: COG1256 Flagellar hook-associated protein; InterPro IPR002371:IPR010930:IPR018247; KEGG: dde:Dde_3152 flagellar hook-associated protein; PFAM: protein of unknown function DUF1078 domain protein; SPTR: Putative uncharacterized protein; TIGRFAM: flagellar hook-associated protein FlgK; IMG reference gene:2505283747; PFAM: Domain of unknown function (DUF1078); TIGRFAM: flagellar hook-associated protein FlgK.
  
    0.609
AEH44757.1
COGs: COG1426 conserved hypothetical protein; KEGG: tte:TTE1826 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284184.
  
    0.574
AEH44606.1
dTDP-glucose 4,6-dehydratase; COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR001509:IPR005888; KEGG: saf:SULAZ_0364 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; IMG reference gene:2505284023; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
 
     0.531
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.512
AEH44569.1
COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: hsm:HSM_0164 glycosyl transferase family protein; PFAM: glycosyl transferase family 2; SPTR: Glycosyltransferase, family 2; IMG reference gene:2505283985; PFAM: Glycosyl transferase family 2.
  
  
 0.451
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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