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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44017.1KEGG: dal:Dalk_0365 GTP-binding protein; SPTR: GTP-binding protein; IMG reference gene:2505283415. (176 aa)    
Predicted Functional Partners:
AEH44018.1
Protein of unknown function DUF343; COGs: COG2835 conserved hypothetical protein; InterPro IPR005651; KEGG: sfu:Sfum_3635 hypothetical protein; PFAM: protein of unknown function DUF343; SPTR: Putative uncharacterized protein; IMG reference gene:2505283416; PFAM: Trm112p-like protein; Belongs to the UPF0434 family.
 
     0.837
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
       0.825
AEH44014.1
COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR014043:IPR004410; KEGG: dak:DaAHT2_1176 malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; SPTR: Malonyl CoA-acyl carrier protein transacylase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; IMG reference gene:2505283412; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase.
       0.559
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
       0.559
AEH45224.1
CoA-substrate-specific enzyme activase; COGs: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); InterPro IPR008275:IPR002731:IPR018709; KEGG: tye:THEYE_A0388 (R)-2-hydroxyglutaryl-CoA dehydratase activator-related protein; PFAM: ATPase BadF/BadG/BcrA/BcrD type; Protein of unknown function DUF2229, CoA enzyme activase; SPTR: Putative uncharacterized protein; TIGRFAM: CoA-substrate-specific enzyme activase; IMG reference gene:2505284671; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; BadF/BadG/BcrA/BcrD ATPase family; CoA enzyme activase uncharact [...]
  
     0.513
AEH44022.1
COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: gme:Gmet_3465 outer membrane efflux protein; PFAM: outer membrane efflux protein; SPTR: Outer membrane efflux protein; IMG reference gene:2505283420; PFAM: Outer membrane efflux protein.
 
     0.503
AEH44013.1
Histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR004358:IPR003594:IPR005467; KEGG: dak:DaAHT2_2152 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Sensory box histidine kinase/response regulator; IMG reference gene:2505283411; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
       0.491
AEH44747.1
InterPro IPR013429; KEGG: dol:Dole_3061 FmdB family regulatory protein; PFAM: Putative regulatory protein FmdB; SPTR: Putative regulatory protein, FmdB family; TIGRFAM: regulatory protein, FmdB family; IMG reference gene:2505284174; PFAM: Zinc ribbon domain; TIGRFAM: putative regulatory protein, FmdB family.
  
     0.484
AEH44019.1
Acriflavin resistance protein; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: dae:Dtox_0522 acriflavin resistance protein; PFAM: acriflavin resistance protein; SPTR: Acriflavin resistance protein; IMG reference gene:2505283417; PFAM: AcrB/AcrD/AcrF family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
       0.439
AEH44020.1
InterPro IPR010462:IPR013096; KEGG: dal:Dalk_1201 cupin 2 conserved barrel domain protein; PFAM: Cupin 2 conserved barrel domain protein; SPTR: Cupin 2 conserved barrel domain protein; IMG reference gene:2505283418; PFAM: Cupin domain.
       0.437
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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