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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44034.1Type II secretion system F domain protein; COGs: COG1459 Type II secretory pathway component PulF; InterPro IPR003004:IPR018076; KEGG: pca:Pcar_2147 putative general protein secretion protein; PFAM: Type II secretion system F domain; SPTR: Putative general protein secretion protein; IMG reference gene:2505283432; PFAM: Bacterial type II secretion system protein F domain. (402 aa)    
Predicted Functional Partners:
AEH44292.1
COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterProIPR001440:IPR007831:IPR001482:IPR019734:IPR 013026:IPR003593; KEGG: sat:SYN_01404 general secretion pathway protein E; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; Tetratricopeptide TPR_1 repeat-containing protein; SMART: AAA ATPase; Tetratricopeptide repeat; SPTR: General secretion pathway protein E; IMG reference gene:2505283699; PFAM: Type II/IV secretion system protein; GSPII_E N-terminal domain.
 
 
 0.938
AEH45742.1
COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterPro IPR001482:IPR007831:IPR003593; KEGG: pmx:PERMA_0977 type IV pilus assembly protein TapB; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; SMART: AAA ATPase; SPTR: Putative uncharacterized protein; IMG reference gene:2505285217; PFAM: GSPII_E N-terminal domain; Type II/IV secretion system protein.
 
 
 0.932
AEH45972.1
COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterPro IPR001482:IPR007831:IPR003593; KEGG: dat:HRM2_30260 GspE3; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; SMART: AAA ATPase; SPTR: GspE3; IMG reference gene:2505285461; PFAM: Type II/IV secretion system protein.
 
 
 0.932
AEH45132.1
Prepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
  
 0.837
AEH44397.1
COGs: COG4972 Tfp pilus assembly protein ATPase PilM; KEGG: dol:Dole_0333 type IV pilus assembly protein PilM; SPTR: Type IV pilus assembly protein PilM; IMG reference gene:2505283809; PFAM: Competence protein A; TIGRFAM: type IV pilus assembly protein PilM.
 
 
 
 0.819
AEH45991.1
Twitching motility protein; COGs: COG2805 Tfp pilus assembly protein pilus retraction ATPase PilT; InterPro IPR003593:IPR001482:IPR006321; KEGG: dak:DaAHT2_1068 twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase; SPTR: Twitching motility protein; TIGRFAM: twitching motility protein; IMG reference gene:2505285480; PFAM: Type II/IV secretion system protein; TIGRFAM: pilus retraction protein PilT.
 
  
 0.787
AEH45990.1
Twitching motility protein; COGs: COG2805 Tfp pilus assembly protein pilus retraction ATPase PilT; InterPro IPR001482:IPR006321; KEGG: dal:Dalk_3301 twitching motility protein; PFAM: type II secretion system protein E; SPTR: Twitching motility protein; TIGRFAM: twitching motility protein; IMG reference gene:2505285479; PFAM: Type II/IV secretion system protein; TIGRFAM: pilus retraction protein PilT.
 
  
 0.786
AEH44393.1
Type IV pilus secretin PilQ; COGs: COG4796 Type II secretory pathway component HofQ; InterPro IPR013355:IPR011662:IPR004846:IPR001775; KEGG: pfo:Pfl01_0409 type II and III secretion system protein; PFAM: type II and III secretion system protein; Secretin/TonB short domain; SPTR: Pilus secretin; TIGRFAM: type IV pilus secretin PilQ; IMG reference gene:2505283805; PFAM: Bacterial type II/III secretion system short domain; Secretin and TonB N terminus short domain; Bacterial type II and III secretion system protein; TIGRFAM: type IV pilus secretin (or competence protein) PilQ.
 
 
 
 0.761
AEH44051.1
DNA internalization-related competence protein ComEC/Rec2; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477:IPR004797; KEGG: nwa:Nwat_0444 DNA internalization-like competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; SPTR: DNA internalization-related competence protein ComEC/Rec2; TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; IMG reference gene:2505283449; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence p [...]
   
  
 0.730
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
       0.601
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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