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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44035.1Protein of unknown function DUF434; COGs: COG2454 conserved hypothetical protein; InterPro IPR007368; KEGG: mfe:Mefer_0862 protein of unknown function DUF434; PFAM: protein of unknown function DUF434; SPTR: Putative uncharacterized protein; IMG reference gene:2505283433; PFAM: Protein of unknown function (DUF434). (235 aa)    
Predicted Functional Partners:
AEH44036.1
COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR003095:IPR001623:IPR002939:IPR018253; KEGG: dak:DaAHT2_1329 chaperone DnaJ domain protein; PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: Chaperone DnaJ domain protein; IMG reference gene:2505283434; PFAM: DnaJ C terminal region; DnaJ domain.
       0.779
AEH45294.1
Hypothetical protein; InterPro IPR015011; KEGG: sfu:Sfum_0182 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505284745; PFAM: Archaea-specific editing domain of threonyl-tRNA synthetase.
  
     0.628
rtcA
RNA 3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
  
     0.504
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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