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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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mltGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (365 aa)    
Predicted Functional Partners:
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
       0.775
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
    0.595
AEH44045.1
Tetratricopeptide TPR_1 repeat-containing protein; InterPro IPR001440:IPR013026:IPR019734; KEGG: nve:NEMVE_v1g201578 hypothetical protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SPTR: Predicted protein; IMG reference gene:2505283443.
       0.565
AEH44043.1
Tetratricopeptide repeat protein; COGs: COG3063 Tfp pilus assembly protein PilF; InterPro IPR019734:IPR013026; KEGG: dak:DaAHT2_1672 TPR repeat-containing protein; SMART: Tetratricopeptide repeat; SPTR: TPR repeat:Tetratricopeptide TPR_4; IMG reference gene:2505283441; PFAM: Tetratricopeptide repeat.
       0.564
AEH44044.1
KEGG: dak:DaAHT2_1673 heat repeat-containing PBS lyase; SPTR: Heat repeat-containing PBS lyase; IMG reference gene:2505283442.
       0.564
AEH45515.1
COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterProIPR019999:IPR005802:IPR018300:IPR001202:IPR 015890:IPR001544; KEGG: dak:DaAHT2_0244 para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding-like; aminotransferase class IV; SPTR: Para-aminobenzoate synthase, component I; TIGRFAM: para-aminobenzoate synthase, subunit I; IMG reference gene:2505284978; PFAM: Aminotransferase class IV; chorismate binding enzyme; TIGRFAM: aminodeoxychorismate synthase, component I, bacterial clade.
  
  
 0.560
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.541
ftsA
Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
 
  
 0.537
AEH44458.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.526
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
 
  
 0.520
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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