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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44083.1Histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR004358:IPR003594:IPR005467; KEGG: dma:DMR_12550 putative sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Histidine kinase; IMG reference gene:2505283481; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (451 aa)    
Predicted Functional Partners:
AEH44948.1
Response regulator receiver sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR020053:IPR001789:IPR003661:IPR003594:IPR 004358:IPR005467; KEGG: cts:Ctha_2310 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SPTR: Putative Histidine kinase; IMG reference gene:2505284387; PFAM: Histidine [...]
 
 
 0.813
AEH44968.1
Putative circadian clock protein, KaiC; COGs: COG0467 RecA-superfamily ATPase implicated in signal transduction; InterPro IPR014774:IPR010624; KEGG: aae:aq_204 hypothetical protein; PFAM: Circadian clock protein KaiC central region; SPTR: Putative uncharacterized protein; IMG reference gene:2505284407; PFAM: KaiC; TIGRFAM: KaiC domain protein, AF_0795 family.
    
 
 0.587
AEH44943.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR003594:IPR001789:IPR004358:IPR 013767:IPR005467; KEGG: ddf:DEFDS_0784 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; response regulator receiver; SPTR: Putative uncharacterized protein; TIGRFAM: PAS sensor protein; IMG reference gene:2505284382; PFAM: Histidine kinase-, DNA gy [...]
 
 
 0.532
AEH44085.1
Proposed homoserine kinase; COGs: COG3635 phosphoglycerate mutase AP superfamily; InterPro IPR019304:IPR006124:IPR013371:IPR004456; KEGG: tye:THEYE_A1682 proposed homoserine kinase; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; metalloenzyme domain protein; PRIAM: Phosphoglycerate mutase; SPTR: Proposed homoserine kinase; TIGRFAM: proposed homoserine kinase; phosphonopyruvate decarboxylase-related protein; IMG reference gene:2505283483; PFAM: Metalloenzyme superfamily; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; TIGRFAM: 2,3-bisphosphoglycerate-ind [...]
 
     0.531
AEH44230.1
CheA signal transduction histidine kinase; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207:IPR004105:IPR003594:IPR002545:IPR 001789:IPR004358:IPR005467; KEGG: dps:DP2642 Che family two-component system sensory/regulatory protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; CheW domain protein; SMART: response regulator receiver; CheW domain protein; ATP-binding region ATPase domain protein; Hpt domain protein; SPTR: Two-component system sensory/r [...]
  
 
 0.530
AEH44020.1
InterPro IPR010462:IPR013096; KEGG: dal:Dalk_1201 cupin 2 conserved barrel domain protein; PFAM: Cupin 2 conserved barrel domain protein; SPTR: Cupin 2 conserved barrel domain protein; IMG reference gene:2505283418; PFAM: Cupin domain.
  
     0.515
AEH44293.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR013767:IPR003661:IPR003594:IPR 004358:IPR005467:IPR000700; KEGG: tye:THEYE_A0125 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Sensor histidine kinase; TIGRFAM: PAS sensor protein; IMG reference gene:2505283700; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like [...]
 
 
 0.511
AEH45584.1
KEGG: dps:DP0127 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505285051.
  
     0.505
AEH46068.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: dba:Dbac_2095 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; IMG reference gene:2505285559; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C [...]
  
 
 0.491
AEH45571.1
KEGG: fpl:Ferp_1555 paREP15, putative coiled-coil protein; SPTR: Putative coiled-coil protein; IMG reference gene:2505285038.
  
     0.470
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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