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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
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AEH44087.1Ammonium transporter; COGs: COG0004 Ammonia permease; InterPro IPR001905:IPR018047; KEGG: slp:Slip_2119 ammonium transporter; PFAM: ammonium transporter; SPTR: Ammonium transporter; TIGRFAM: ammonium transporter; IMG reference gene:2505283485; PFAM: Ammonium Transporter Family; TIGRFAM: ammonium transporter. (455 aa)    
Predicted Functional Partners:
AEH46046.1
COGs: COG0347 Nitrogen regulatory protein PII; InterPro IPR002187:IPR002332:IPR017918; KEGG: pmx:PERMA_1585 nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein P-II; SPTR: Nitrogen regulatory protein P-II; IMG reference gene:2505285535; PFAM: Nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
 
 0.975
AEH44088.1
COGs: COG0347 Nitrogen regulatory protein PII; InterPro IPR002187:IPR017918; KEGG: dth:DICTH_0174 nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein P-II; SPTR: Nitrogen regulatory protein P-II; IMG reference gene:2505283486; PFAM: Nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
 
 
 0.951
AEH44922.1
COGs: COG0347 Nitrogen regulatory protein PII; InterPro IPR017918:IPR002187; KEGG: mba:Mbar_A2279 P-II family nitrogen regulatory protein; PFAM: nitrogen regulatory protein P-II; SPTR: Nitrogen regulatory protein P-II; IMG reference gene:2505284361; PFAM: Nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
 
 
 0.786
AEH44921.1
COGs: COG0347 Nitrogen regulatory protein PII; InterPro IPR017918:IPR002187; KEGG: mfs:MFS40622_0032 nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein P-II; SPTR: Nitrogen regulatory protein P-II; IMG reference gene:2505284360; PFAM: Nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
 
 
 0.773
AEH44973.1
COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterProIPR003661:IPR003594:IPR001789:IPR004358:IPR 000014:IPR005467; KEGG: ddf:DEFDS_0784 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SPTR: Putative uncharacterized protein; TIGRFAM: PAS sensor protein; IMG reference gene:2505284412; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator re [...]
  
 
 0.525
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.509
AEH46025.1
Formate dehydrogenase, alpha subunit; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR000759:IPR001041:IPR013027:IPR006963:IPR 006656:IPR006657:IPR018247:IPR017900:IPR006655:IPR017896:I PR006478; KEGG: dak:DaAHT2_0823 formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; ferredoxin; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; SPTR: Formate dehydrogenase, alpha subunit; TIGRFAM: formate dehydrogenase, alpha subunit; manually curated; selenocysteine- [...]
  
  
 0.497
AEH45731.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR003661:IPR003594:IPR005467; KEGG: drm:Dred_1311 sensory histidine kinase AtoS; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Signal transduction histidine-protein kinase atoS; IMG reference gene:2505285206; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
  
 
 0.483
nifH
Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
   
  
 0.468
AEH44795.1
COGs: COG0069 Glutamate synthase domain 2; InterPro IPR017900:IPR002932:IPR017896; KEGG: dde:Dde_1814 glutamate synthase (NADPH) GltB2 subunit; PFAM: ferredoxin-dependent glutamate synthase; PRIAM: Glutamate synthase (NADPH); SPTR: Glutamate synthase (NADPH) GltB2 subunit; IMG reference gene:2505284226; PFAM: 4Fe-4S binding domain; Conserved region in glutamate synthase; Belongs to the glutamate synthase family.
 
  
 0.463
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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