Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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co-expression
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AEH44088.1COGs: COG0347 Nitrogen regulatory protein PII; InterPro IPR002187:IPR017918; KEGG: dth:DICTH_0174 nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein P-II; SPTR: Nitrogen regulatory protein P-II; IMG reference gene:2505283486; PFAM: Nitrogen regulatory protein P-II; Belongs to the P(II) protein family. (112 aa)    
Predicted Functional Partners:
AEH44087.1
Ammonium transporter; COGs: COG0004 Ammonia permease; InterPro IPR001905:IPR018047; KEGG: slp:Slip_2119 ammonium transporter; PFAM: ammonium transporter; SPTR: Ammonium transporter; TIGRFAM: ammonium transporter; IMG reference gene:2505283485; PFAM: Ammonium Transporter Family; TIGRFAM: ammonium transporter.
 
 
 0.951
glnD
UTP-GlnB uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
 
 
 0.949
AEH46046.1
COGs: COG0347 Nitrogen regulatory protein PII; InterPro IPR002187:IPR002332:IPR017918; KEGG: pmx:PERMA_1585 nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein P-II; SPTR: Nitrogen regulatory protein P-II; IMG reference gene:2505285535; PFAM: Nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
  
  
 
0.904
AEH45358.1
Ammonium transporter; COGs: COG0004 Ammonia permease; InterPro IPR001905:IPR018047; KEGG: drt:Dret_2267 ammonium transporter; PFAM: ammonium transporter; SPTR: Ammonium transporter; TIGRFAM: ammonium transporter; IMG reference gene:2505284814; PFAM: Ammonium Transporter Family; TIGRFAM: ammonium transporter.
 
 
 0.768
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
    
 
 0.731
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.468
AEH44973.1
COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterProIPR003661:IPR003594:IPR001789:IPR004358:IPR 000014:IPR005467; KEGG: ddf:DEFDS_0784 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SPTR: Putative uncharacterized protein; TIGRFAM: PAS sensor protein; IMG reference gene:2505284412; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator re [...]
  
 
 0.424
AEH44084.1
COGs: COG1047 FKBP-type peptidyl-prolyl cis-trans isomerase 2; InterPro IPR001179; KEGG: pmy:Pmen_0955 peptidylprolyl isomerase, FKBP-type; PFAM: peptidylprolyl isomerase FKBP-type; SPTR: Peptidyl-prolyl cis-trans isomerase; IMG reference gene:2505283482; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase.
  
    0.415
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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