close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44142.1COGs: COG0760 Parvulin-like peptidyl-prolyl isomerase; InterPro IPR000297; KEGG: dol:Dole_0268 PpiC-type peptidyl-prolyl cis-trans isomerase; PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SPTR: PpiC-type peptidyl-prolyl cis-trans isomerase; IMG reference gene:2505283542; PFAM: SurA N-terminal domain; PPIC-type PPIASE domain. (628 aa)    
Predicted Functional Partners:
carB
COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR005483:IPR005481:IPR005479:IPR005480:IPR 011607:IPR011761:IPR006275; KEGG: dal:Dalk_3481 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; SPTR: Carbamoyl-phosphate synthase, large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; IMG reference gene:2505283541; PFAM: Carbamoyl-phosphate synthase L cha [...]
   
   0.823
AEH44140.1
AAA-ATPase; InterPro IPR018631:IPR012547; KEGG: saf:SULAZ_0155 conserved protein, with A weak D-galactarate dehydratase/altronate hydrolase domain; PFAM: AAA-ATPase-like; protein of unknown function DUF1703; SPTR: Conserved protein, with A weak D-galactarate dehydratase/altronate hydrolase domain; IMG reference gene:2505283540; PFAM: Protein of unknown function (DUF1703); Predicted AAA-ATPase.
       0.746
AEH44144.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358:IPR013655:IPR003661:IPR003594:IPR 001789:IPR005467:IPR000014:IPR000700; KEGG: dak:DaAHT2_2564 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; histidine kinase A domain protein; response regulator receiver; SPTR: Multi-sensor hyb [...]
  
  
 0.657
AEH44143.1
Glycoside hydrolase family 3 domain protein; COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764; KEGG: dak:DaAHT2_2367 glycoside hydrolase family 3 domain protein; PFAM: glycoside hydrolase family 3 domain protein; SPTR: Glycoside hydrolase family 3 domain protein; IMG reference gene:2505283543; PFAM: Glycosyl hydrolase family 3 N terminal domain.
       0.635
AEH44684.1
COGs: COG1452 Organic solvent tolerance protein OstA; InterPro IPR007543; KEGG: drt:Dret_1088 organic solvent tolerance protein; PFAM: Organic solvent tolerance protein; SPTR: Organic solvent tolerance protein; IMG reference gene:2505284103; PFAM: Organic solvent tolerance protein.
 
  
 0.631
AEH45175.1
Tol-pal system protein YbgF; COGs: COG1729 conserved hypothetical protein; InterPro IPR014162:IPR019734:IPR013026; KEGG: gbm:Gbem_3515 tol-pal system protein YbgF; SMART: Tetratricopeptide repeat; SPTR: Tol-pal system protein YbgF; TIGRFAM: tol-pal system protein YbgF; IMG reference gene:2505284622; PFAM: Tetratricopeptide repeat; TIGRFAM: tol-pal system protein YbgF.
  
    0.557
AEH45020.1
Outer membrane assembly lipoprotein YfiO; COGs: COG4105 DNA uptake lipoprotein; InterPro IPR017689:IPR013026; KEGG: dal:Dalk_2404 outer membrane assembly lipoprotein YfiO; SPTR: Outer membrane assembly lipoprotein YfiO; TIGRFAM: outer membrane assembly lipoprotein YfiO; IMG reference gene:2505284462; TIGRFAM: outer membrane assembly lipoprotein YfiO.
  
  
 0.540
yidC
Membrane protein insertase, YidC/Oxa1 family; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
  
  
 0.499
AEH44486.1
Lipoprotein releasing system, transmembrane protein, LolC/E family; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR011925:IPR003838; KEGG: sfu:Sfum_3743 LolC/E family lipoprotein releasing system, transmembrane protein; PFAM: protein of unknown function DUF214; SPTR: Lipoprotein releasing system, transmembrane protein, LolC/E family; TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; IMG reference gene:2505283900; PFAM: Predicted permease; TIGRFAM: lipoprotein releasing system, transmembrane protein, Lol [...]
  
     0.496
secF
Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
  
  
 0.459
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: low (34%) [HD]