Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH44142.1COGs: COG0760 Parvulin-like peptidyl-prolyl isomerase; InterPro IPR000297; KEGG: dol:Dole_0268 PpiC-type peptidyl-prolyl cis-trans isomerase; PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SPTR: PpiC-type peptidyl-prolyl cis-trans isomerase; IMG reference gene:2505283542; PFAM: SurA N-terminal domain; PPIC-type PPIASE domain. (628 aa)    
Predicted Functional Partners:
AEH45662.1
Hypothetical protein; InterPro IPR019734:IPR013026; KEGG: dak:DaAHT2_1194 tetratricopeptide TPR_4; SPTR: Tetratricopeptide TPR_4; IMG reference gene:2505285133.
 
 
 0.834
carB
COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR005483:IPR005481:IPR005479:IPR005480:IPR 011607:IPR011761:IPR006275; KEGG: dal:Dalk_3481 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; SPTR: Carbamoyl-phosphate synthase, large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; IMG reference gene:2505283541; PFAM: Carbamoyl-phosphate synthase L cha [...]
   
   0.808
AEH44140.1
AAA-ATPase; InterPro IPR018631:IPR012547; KEGG: saf:SULAZ_0155 conserved protein, with A weak D-galactarate dehydratase/altronate hydrolase domain; PFAM: AAA-ATPase-like; protein of unknown function DUF1703; SPTR: Conserved protein, with A weak D-galactarate dehydratase/altronate hydrolase domain; IMG reference gene:2505283540; PFAM: Protein of unknown function (DUF1703); Predicted AAA-ATPase.
       0.746
AEH44144.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358:IPR013655:IPR003661:IPR003594:IPR 001789:IPR005467:IPR000014:IPR000700; KEGG: dak:DaAHT2_2564 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; histidine kinase A domain protein; response regulator receiver; SPTR: Multi-sensor hyb [...]
     
 0.647
AEH45175.1
Tol-pal system protein YbgF; COGs: COG1729 conserved hypothetical protein; InterPro IPR014162:IPR019734:IPR013026; KEGG: gbm:Gbem_3515 tol-pal system protein YbgF; SMART: Tetratricopeptide repeat; SPTR: Tol-pal system protein YbgF; TIGRFAM: tol-pal system protein YbgF; IMG reference gene:2505284622; PFAM: Tetratricopeptide repeat; TIGRFAM: tol-pal system protein YbgF.
  
   0.647
AEH44143.1
Glycoside hydrolase family 3 domain protein; COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764; KEGG: dak:DaAHT2_2367 glycoside hydrolase family 3 domain protein; PFAM: glycoside hydrolase family 3 domain protein; SPTR: Glycoside hydrolase family 3 domain protein; IMG reference gene:2505283543; PFAM: Glycosyl hydrolase family 3 N terminal domain.
       0.633
AEH44684.1
COGs: COG1452 Organic solvent tolerance protein OstA; InterPro IPR007543; KEGG: drt:Dret_1088 organic solvent tolerance protein; PFAM: Organic solvent tolerance protein; SPTR: Organic solvent tolerance protein; IMG reference gene:2505284103; PFAM: Organic solvent tolerance protein.
 
  
 0.630
AEH45020.1
Outer membrane assembly lipoprotein YfiO; COGs: COG4105 DNA uptake lipoprotein; InterPro IPR017689:IPR013026; KEGG: dal:Dalk_2404 outer membrane assembly lipoprotein YfiO; SPTR: Outer membrane assembly lipoprotein YfiO; TIGRFAM: outer membrane assembly lipoprotein YfiO; IMG reference gene:2505284462; TIGRFAM: outer membrane assembly lipoprotein YfiO.
  
 
 0.624
AEH44484.1
COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR016474:IPR010827:IPR000184; KEGG: dak:DaAHT2_1309 outer membrane protein assembly complex, YaeT protein; PFAM: surface antigen (D15); surface antigen variable number repeat-containing protein; SPTR: Surface antigen (D15):Surface antigen variable number; TIGRFAM: outer membrane protein assembly complex, YaeT protein; IMG reference gene:2505283898; PFAM: Surface antigen variable number repeat; Surface antigen; TIGRFAM: outer membrane protein assembly complex, YaeT protein.
 
 
 0.532
secF
Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
  
  
 0.518
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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