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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44148.1D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: pfs:PFLU3778 D-lactate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: Probable D-lactate dehydrogenase; IMG reference gene:2505283548; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (325 aa)    
Predicted Functional Partners:
AEH45096.1
COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: dak:DaAHT2_0323 hydroxyacylglutathione hydrolase; SPTR: Beta-lactamase-like; IMG reference gene:2505284541; PFAM: Metallo-beta-lactamase superfamily.
   
 0.910
AEH43910.1
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.909
AEH45275.1
COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR002192:IPR008279; KEGG: dak:DaAHT2_2096 pyruvate phosphate dikinase PEP/pyruvate-binding protein; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; SPTR: Pyruvate phosphate dikinase PEP/pyruvate-binding protein; IMG reference gene:2505284724; PFAM: PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain.
    
 0.909
AEH45915.1
COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR002192:IPR008279; KEGG: dvm:DvMF_0705 pyruvate, water dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; SPTR: Pyruvate, water dikinase; IMG reference gene:2505285402; PFAM: PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain.
    
 0.909
AEH44844.1
COGs: COG1038 Pyruvate carboxylase; InterPro IPR001882:IPR000891:IPR003379:IPR000089; KEGG: cts:Ctha_2637 oxaloacetate decarboxylase; PFAM: biotin/lipoyl attachment domain-containing protein; Conserved carboxylase region; pyruvate carboxyltransferase; PRIAM: Pyruvate carboxylase; SPTR: Oxaloacetate decarboxylase; IMG reference gene:2505284281; PFAM: HMGL-like; Biotin-requiring enzyme; Conserved carboxylase domain.
   
 
 0.905
AEH45286.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880; KEGG: sat:SYN_00155 pyruvate:ferredoxin oxidoreductase alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: Pyruvate:ferredoxin oxidoreductase alpha subunit; IMG reference gene:2505284735; PFAM: domain.
    
  0.904
AEH45287.1
Thiamine pyrophosphate TPP-binding domain-containing protein; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: sfu:Sfum_2795 thiamine pyrophosphate binding domain-containing protein; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin oxidoreductase, beta subunit; IMG reference gene:2505284736; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
    
  0.904
AEH45284.1
Pyruvate/ketoisovalerate oxidoreductase, gamma subunit; COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR011894:IPR019752; KEGG: sat:SYN_00157 pyruvate:ferredoxin oxidoreductase gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; SPTR: Pyruvate:ferredoxin oxidoreductase gamma subunit; TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; IMG reference gene:2505284733; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subu [...]
     
  0.900
AEH45285.1
COGs: COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase delta subunit; InterPro IPR011898:IPR017900:IPR017896; KEGG: sfu:Sfum_2793 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; SPTR: Pyruvate ferredoxin oxidoreductase, delta subunit; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; IMG reference gene:2505284734; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family.
     
  0.900
AEH45773.1
Acetolactate synthase, large subunit, biosynthetic type; COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterProIPR000399:IPR012001:IPR012000:IPR011766:IPR 012846; KEGG: tye:THEYE_A1275 acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; thiamine pyrophosphate central domain-containing protein; SPTR: Acetolactate synthase; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; IMG reference gene:2505285253; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-te [...]
  
 
 0.831
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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