node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEH44148.1 | AEH44152.1 | Thein_0264 | Thein_0268 | D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: pfs:PFLU3778 D-lactate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: Probable D-lactate dehydrogenase; IMG reference gene:2505283548; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | AsmA family protein; InterPro IPR007844; KEGG: sfu:Sfum_3774 membrane protein-like; PFAM: AsmA family protein; SPTR: Membrane protein-like; IMG reference gene:2505283553; PFAM: AsmA family. | 0.481 |
AEH44148.1 | AEH44153.1 | Thein_0264 | Thein_0269 | D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: pfs:PFLU3778 D-lactate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: Probable D-lactate dehydrogenase; IMG reference gene:2505283548; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: nfa:nfa6770 ATP-dependent DNA ligase; SPTR: Putative ATP-dependent DNA ligase; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; IMG reference gene:2505283554; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain. | 0.481 |
AEH44148.1 | ispD | Thein_0264 | Thein_0265 | D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: pfs:PFLU3778 D-lactate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: Probable D-lactate dehydrogenase; IMG reference gene:2505283548; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.779 |
AEH44148.1 | nfi | Thein_0264 | Thein_0266 | D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: pfs:PFLU3778 D-lactate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: Probable D-lactate dehydrogenase; IMG reference gene:2505283548; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | Deoxyribonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. | 0.786 |
AEH44152.1 | AEH44148.1 | Thein_0268 | Thein_0264 | AsmA family protein; InterPro IPR007844; KEGG: sfu:Sfum_3774 membrane protein-like; PFAM: AsmA family protein; SPTR: Membrane protein-like; IMG reference gene:2505283553; PFAM: AsmA family. | D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: pfs:PFLU3778 D-lactate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: Probable D-lactate dehydrogenase; IMG reference gene:2505283548; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | 0.481 |
AEH44152.1 | AEH44153.1 | Thein_0268 | Thein_0269 | AsmA family protein; InterPro IPR007844; KEGG: sfu:Sfum_3774 membrane protein-like; PFAM: AsmA family protein; SPTR: Membrane protein-like; IMG reference gene:2505283553; PFAM: AsmA family. | DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: nfa:nfa6770 ATP-dependent DNA ligase; SPTR: Putative ATP-dependent DNA ligase; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; IMG reference gene:2505283554; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain. | 0.773 |
AEH44152.1 | ispD | Thein_0268 | Thein_0265 | AsmA family protein; InterPro IPR007844; KEGG: sfu:Sfum_3774 membrane protein-like; PFAM: AsmA family protein; SPTR: Membrane protein-like; IMG reference gene:2505283553; PFAM: AsmA family. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.481 |
AEH44152.1 | nfi | Thein_0268 | Thein_0266 | AsmA family protein; InterPro IPR007844; KEGG: sfu:Sfum_3774 membrane protein-like; PFAM: AsmA family protein; SPTR: Membrane protein-like; IMG reference gene:2505283553; PFAM: AsmA family. | Deoxyribonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. | 0.481 |
AEH44153.1 | AEH44148.1 | Thein_0269 | Thein_0264 | DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: nfa:nfa6770 ATP-dependent DNA ligase; SPTR: Putative ATP-dependent DNA ligase; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; IMG reference gene:2505283554; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain. | D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: pfs:PFLU3778 D-lactate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: Probable D-lactate dehydrogenase; IMG reference gene:2505283548; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | 0.481 |
AEH44153.1 | AEH44152.1 | Thein_0269 | Thein_0268 | DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: nfa:nfa6770 ATP-dependent DNA ligase; SPTR: Putative ATP-dependent DNA ligase; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; IMG reference gene:2505283554; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain. | AsmA family protein; InterPro IPR007844; KEGG: sfu:Sfum_3774 membrane protein-like; PFAM: AsmA family protein; SPTR: Membrane protein-like; IMG reference gene:2505283553; PFAM: AsmA family. | 0.773 |
AEH44153.1 | AEH44875.1 | Thein_0269 | Thein_1003 | DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: nfa:nfa6770 ATP-dependent DNA ligase; SPTR: Putative ATP-dependent DNA ligase; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; IMG reference gene:2505283554; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.878 |
AEH44153.1 | AEH44929.1 | Thein_0269 | Thein_1058 | DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: nfa:nfa6770 ATP-dependent DNA ligase; SPTR: Putative ATP-dependent DNA ligase; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; IMG reference gene:2505283554; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain. | COGs: COG0708 Exonuclease III; InterPro IPR005135:IPR000097:IPR004808; KEGG: gvi:glr0140 exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; PRIAM: Exodeoxyribonuclease III; SPTR: Exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; IMG reference gene:2505284368; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth). | 0.527 |
AEH44153.1 | AEH44982.1 | Thein_0269 | Thein_1111 | DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: nfa:nfa6770 ATP-dependent DNA ligase; SPTR: Putative ATP-dependent DNA ligase; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; IMG reference gene:2505283554; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain. | PHP domain protein; COGs: COG1796 DNA polymerase IV (family X); InterProIPR002054:IPR003583:IPR003141:IPR002008:IPR 004013; KEGG: adg:Adeg_1792 DNA-directed DNA polymerase; PFAM: PHP domain protein; SMART: DNA polymerase X; Helix-hairpin-helix DNA-binding class 1; phosphoesterase PHP domain protein; SPTR: DNA-directed DNA polymerase; IMG reference gene:2505284421; PFAM: PHP domain. | 0.781 |
AEH44153.1 | AEH45292.1 | Thein_0269 | Thein_1426 | DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: nfa:nfa6770 ATP-dependent DNA ligase; SPTR: Putative ATP-dependent DNA ligase; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; IMG reference gene:2505283554; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain. | DNA polymerase LigD, ligase domain protein; COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR014146:IPR012310:IPR012309:IPR016059; KEGG: mta:Moth_1488 ATP dependent DNA ligase, central; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; SPTR: ATP dependent DNA ligase, central; TIGRFAM: DNA polymerase LigD, ligase domain protein; IMG reference gene:2505284743; PFAM: ATP dependent DNA ligase domain; ATP dependent DNA ligase C terminal region; TIGRFAM: DNA polymerase LigD, ligase domain. | 0.975 |
AEH44153.1 | ispD | Thein_0269 | Thein_0265 | DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: nfa:nfa6770 ATP-dependent DNA ligase; SPTR: Putative ATP-dependent DNA ligase; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; IMG reference gene:2505283554; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.481 |
AEH44153.1 | ku | Thein_0269 | Thein_1425 | DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: nfa:nfa6770 ATP-dependent DNA ligase; SPTR: Putative ATP-dependent DNA ligase; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; IMG reference gene:2505283554; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain. | Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.827 |
AEH44153.1 | nfi | Thein_0269 | Thein_0266 | DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: nfa:nfa6770 ATP-dependent DNA ligase; SPTR: Putative ATP-dependent DNA ligase; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; IMG reference gene:2505283554; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain. | Deoxyribonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. | 0.481 |
AEH44153.1 | polA | Thein_0269 | Thein_1717 | DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: nfa:nfa6770 ATP-dependent DNA ligase; SPTR: Putative ATP-dependent DNA ligase; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; IMG reference gene:2505283554; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.840 |
AEH44875.1 | AEH44153.1 | Thein_1003 | Thein_0269 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: nfa:nfa6770 ATP-dependent DNA ligase; SPTR: Putative ATP-dependent DNA ligase; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; IMG reference gene:2505283554; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain. | 0.878 |
AEH44875.1 | AEH44929.1 | Thein_1003 | Thein_1058 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | COGs: COG0708 Exonuclease III; InterPro IPR005135:IPR000097:IPR004808; KEGG: gvi:glr0140 exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; PRIAM: Exodeoxyribonuclease III; SPTR: Exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; IMG reference gene:2505284368; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth). | 0.971 |