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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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AEH44173.1COGs: COG0374 Ni Fe-hydrogenase I large subunit; InterPro IPR001501:IPR018194; KEGG: dps:DP0575 Ni/Fe-hydrogenase, large subunit; PFAM: nickel-dependent hydrogenase large subunit; SPTR: Probable Ni/Fe-hydrogenase, large subunit; IMG reference gene:2505283578; PFAM: Nickel-dependent hydrogenase; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (566 aa)    
Predicted Functional Partners:
AEH44174.1
COGs: COG1740 Ni Fe-hydrogenase I small subunit; InterPro IPR001821:IPR006137:IPR017909:IPR006311; KEGG: dps:DP0574 Ni/Fe-hydrogenase, small subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; PRIAM: Hydrogenase (acceptor); SPTR: Probable Ni/Fe-hydrogenase, small subunit; TIGRFAM: hydrogenase (NiFe) small subunit HydA; IMG reference gene:2505283579; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: hydrogenase (NiFe) small subunit (hydA); Tat (twin-arginine translocation) pathway signal sequence.
 
 
 0.998
AEH44172.1
COGs: COG1969 Ni Fe-hydrogenase I cytochrome b subunit; InterPro IPR000516; KEGG: dps:DP0576 Ni/Fe-hydrogenase, cytochrome subunit; SPTR: Probable Ni/Fe-hydrogenase, cytochrome subunit; TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; IMG reference gene:2505283577; PFAM: Cytochrome b(N-terminal)/b6/petB; TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit.
 
 
 0.992
hypA
Hydrogenase expression/synthesis HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.968
AEH44175.1
COGs: COG0680 Ni Fe-hydrogenase maturation factor; InterPro IPR000671; KEGG: tjr:TherJR_0260 hydrogenase maturation protease; PFAM: peptidase M52 hydrogen uptake protein; SPTR: Hydrogenase maturation protease; TIGRFAM: hydrogenase maturation protease; IMG reference gene:2505283580; PFAM: Hydrogenase maturation protease; TIGRFAM: hydrogenase expression/formation protein; hydrogenase maturation protease.
 
  
 0.921
AEH44167.1
Methyl-viologen-reducing hydrogenase delta subunit; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterProIPR013027:IPR003953:IPR001327:IPR003813:IPR 017896:IPR017900; KEGG: afu:AF0662 heterodisulfide reductase, subunit A/methylviologen reducing hydrogenase, subunit delta; PFAM: methyl-viologen-reducing hydrogenase delta subunit; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Methyl-viologen-reducing hydrogenase delta subunit; IMG reference gene:2505283572; PFAM: [...]
  
 
 0.917
AEH44627.1
Methyl-viologen-reducing hydrogenase delta subunit; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterProIPR017896:IPR013027:IPR006076:IPR003813:IPR 017900; KEGG: apo:Arcpr_0774 methyl-viologen-reducing hydrogenase delta subunit; PFAM: methyl-viologen-reducing hydrogenase delta subunit; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; SPTR: Methyl-viologen-reducing hydrogenase delta subunit; IMG reference gene:2505284045; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit; Pyridine nucleotide-disulphide [...]
  
 
 0.917
AEH45286.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880; KEGG: sat:SYN_00155 pyruvate:ferredoxin oxidoreductase alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: Pyruvate:ferredoxin oxidoreductase alpha subunit; IMG reference gene:2505284735; PFAM: domain.
     
 0.912
AEH45287.1
Thiamine pyrophosphate TPP-binding domain-containing protein; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: sfu:Sfum_2795 thiamine pyrophosphate binding domain-containing protein; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin oxidoreductase, beta subunit; IMG reference gene:2505284736; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
     
 0.912
AEH45285.1
COGs: COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase delta subunit; InterPro IPR011898:IPR017900:IPR017896; KEGG: sfu:Sfum_2793 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; SPTR: Pyruvate ferredoxin oxidoreductase, delta subunit; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; IMG reference gene:2505284734; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family.
     
 0.908
AEH45284.1
Pyruvate/ketoisovalerate oxidoreductase, gamma subunit; COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR011894:IPR019752; KEGG: sat:SYN_00157 pyruvate:ferredoxin oxidoreductase gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; SPTR: Pyruvate:ferredoxin oxidoreductase gamma subunit; TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; IMG reference gene:2505284733; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subu [...]
     
 0.906
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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