close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44185.1Cobyrinic acid ac-diamide synthase; COGs: COG3640 CO dehydrogenase maturation factor; InterPro IPR014433; KEGG: dak:DaAHT2_1179 cobyrinic acid ac-diamide synthase; SPTR: Cobyrinic acid a,c-diamide synthase; IMG reference gene:2505283590; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain. (254 aa)    
Predicted Functional Partners:
AEH46031.1
COGs: COG1614 CO dehydrogenase/acetyl-CoA synthase beta subunit; InterPro IPR004461; KEGG: dak:DaAHT2_0825 CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase complex beta subunit; PRIAM: CO-methylating acetyl-CoA synthase; SPTR: CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; TIGRFAM: CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; IMG reference gene:2505285520; PFAM: CO dehydrogenase/acetyl-CoA synthase complex beta subunit; TIGRFAM: CO dehydrogenase/CO-methylating acetyl-CoA synthase complex, beta subunit.
 
  
 0.957
AEH46032.1
COGs: COG2069 CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein); InterPro IPR019734:IPR003171:IPR016041:IPR013026; KEGG: dak:DaAHT2_0826 CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; methylenetetrahydrofolate reductase; SPTR: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; IMG reference gene:2505285521; PFAM: Methylenetetrahydrofolate reductase; CO dehydrogenase/acetyl-CoA synthase delta subunit; TIGRFAM: CO dehydrogenase/acetyl-CoA synthase, delta subunit.
 
  
 0.910
AEH46030.1
CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; COGs: COG1456 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein); InterPro IPR007202:IPR016041:IPR016218; KEGG: dak:DaAHT2_0824 CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; Fe-S cluster domain protein; SPTR: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; IMG reference gene:2505285519; PFAM: Putative Fe-S cluster; CO dehydrogenase/acetyl-CoA synthase delta subunit.
 
  
 0.827
AEH44186.1
2-isopropylmalate synthase/homocitrate synthase family protein; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891:IPR013709:IPR005675:IPR002034; KEGG: sfu:Sfum_2174 putative alpha-isopropylmalate/homocitrate synthase family transferase; PFAM: LeuA allosteric (dimerisation) domain-containing protein; pyruvate carboxyltransferase; SPTR: 2-isopropylmalate synthase; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; IMG reference gene:2505283591; PFAM: HMGL-like; LeuA allosteric (dimerisation) domain; TIGRFAM: 2-isopropylmalate synthas [...]
       0.825
AEH45313.1
InterPro IPR007202; KEGG: dak:DaAHT2_0716 Fe-S cluster domain protein; PFAM: Fe-S cluster domain protein; SPTR: Putative Fe-S cluster; IMG reference gene:2505284768; PFAM: Putative Fe-S cluster.
 
  
 0.825
AEH44187.1
COGs: COG0527 Aspartokinase; InterProIPR005260:IPR001341:IPR001048:IPR002912:IPR 001057:IPR018042; KEGG: pca:Pcar_1006 aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; SPTR: Aspartokinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; IMG reference gene:2505283592; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family.
       0.813
AEH44188.1
InterPro IPR001623:IPR003095; KEGG: mhu:Mhun_0257 heat shock protein DnaJ-like; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: Heat shock protein DnaJ-like; IMG reference gene:2505283593; PFAM: DnaJ domain.
       0.813
AEH46038.1
Carbon-monoxide dehydrogenase, catalytic subunit; COGs: COG1151 6Fe-6S prismane cluster-containing protein; InterPro IPR004137:IPR010047; KEGG: adg:Adeg_0335 carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane; PRIAM: Carbon-monoxide dehydrogenase (acceptor); SPTR: Carbon-monoxide dehydrogenase, catalytic subunit; TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit; IMG reference gene:2505285527; PFAM: Prismane/CO dehydrogenase family; TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit.
 
   
 0.784
AEH45288.1
Carbon-monoxide dehydrogenase, catalytic subunit; COGs: COG1151 6Fe-6S prismane cluster-containing protein; InterPro IPR010047:IPR004137; KEGG: pca:Pcar_0057 carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane; PRIAM: Carbon-monoxide dehydrogenase (acceptor); SPTR: Carbon-monoxide dehydrogenase, catalytic subunit; TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit; IMG reference gene:2505284738; PFAM: Prismane/CO dehydrogenase family; TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit.
 
   
 0.783
AEH44110.1
Fe-S cluster domain protein; COGs: COG4871 conserved hypothetical protein; InterPro IPR007202; KEGG: afu:AF2246 hypothetical protein; PFAM: Fe-S cluster domain protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505283509; PFAM: Putative Fe-S cluster.
  
     0.774
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.