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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44200.1DNA binding domain protein, excisionase family; COGs: COG1910 Periplasmic molybdate-binding protein/domain; InterPro IPR010093:IPR000551; KEGG: dak:DaAHT2_2633 DNA binding domain protein, excisionase family; PFAM: regulatory protein MerR; SPTR: DNA binding domain protein, excisionase family; TIGRFAM: DNA binding domain protein, excisionase family; IMG reference gene:2505283605; TIGRFAM: DNA binding domain, excisionase family. (307 aa)    
Predicted Functional Partners:
AEH45708.1
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
    0.945
AEH44201.1
ABC transporter, periplasmic substrate-binding protein; COGs: COG2998 ABC-type tungstate transport system permease component; KEGG: aco:Amico_1561 ABC transporter, periplasmic substrate-binding protein; SPTR: Tungstate ABC transporter, tungstate-binding protein; IMG reference gene:2505283606.
 
     0.911
AEH44202.1
Binding-protein-dependent transport systems inner membrane component; COGs: COG4662 ABC-type tungstate transport system periplasmic component; InterPro IPR000515; KEGG: dat:HRM2_17610 predicted ABC-type molybdate/tungstate transporter, permease component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Predicted ABC-type molybdate/tungstate transporter, permease component; IMG reference gene:2505283607; PFAM: Binding-protein-dependent transport system inner membrane component.
 
    0.864
AEH45727.1
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
    0.769
fdhD
Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
     0.590
AEH45679.1
Polyferredoxin; InterPro IPR017896:IPR017900; KEGG: dps:DP1772 polyferredoxins; SPTR: Related to polyferredoxins; IMG reference gene:2505285150; PFAM: 4Fe-4S binding domain.
 
     0.542
AEH45678.1
Hypothetical protein; COGs: COG3381 Uncharacterized component of anaerobic dehydrogenase; InterPro IPR001849; KEGG: ddf:DEFDS_1333 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505285149; PFAM: Nitrate reductase delta subunit.
 
    0.533
AEH45676.1
Nitrate reductase; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterProIPR006311:IPR017909:IPR006655:IPR006963:IPR 006656:IPR006657; KEGG: ddf:DEFDS_1331 formate dehydrogenase subunit alpha; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; PRIAM: Nitrate reductase; SPTR: Formate dehydrogenase, alpha subunit; manually curated; selenocysteine-containing protein; IMG reference gene:2505285147; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxi [...]
 
     0.507
AEH45958.1
COGs: COG2414 Aldehyde:ferredoxin oxidoreductase; InterPro IPR013983:IPR001203; KEGG: cpo:COPRO5265_0137 tungsten-containing aldehyde ferredoxin oxidoreductase; PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; PRIAM: Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase; SPTR: Tungsten-containing aldehyde ferredoxin oxidoreductase; IMG reference gene:2505285447; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal domain; Aldehyde ferredoxin oxidoreductase, domains 2 & 3.
 
     0.488
AEH45956.1
COGs: COG2414 Aldehyde:ferredoxin oxidoreductase; InterPro IPR013983:IPR001203; KEGG: tye:THEYE_A0591 aldehyde ferredoxin oxidoreductase; PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; PRIAM: Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase; SPTR: Aldehyde ferredoxin oxidoreductase; IMG reference gene:2505285445; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal domain; Aldehyde ferredoxin oxidoreductase, domains 2 & 3.
 
     0.484
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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