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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44227.1HNH endonuclease; COGs: COG1403 Restriction endonuclease; InterPro IPR002711:IPR003615; KEGG: ade:Adeh_1905 HNH endonuclease; PFAM: HNH endonuclease; SMART: HNH nuclease; SPTR: HNH endonuclease; IMG reference gene:2505283633; PFAM: HNH endonuclease. (203 aa)    
Predicted Functional Partners:
AEH45821.1
KEGG: gsu:GSU2122 TraG family protein; SPTR: TraG family protein; IMG reference gene:2505285303; PFAM: TraG/TraD family.
   
 
 0.630
purL
Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...]
  
    0.618
AEH44226.1
Protein of unknown function DUF89; COGs: COG1578 conserved hypothetical protein; InterPro IPR002791:IPR014444; KEGG: adg:Adeg_0546 protein of unknown function DUF89; PFAM: protein of unknown function DUF89; SPTR: Putative uncharacterized protein; IMG reference gene:2505283632; PFAM: Protein of unknown function DUF89.
       0.449
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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