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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44244.1Radical SAM domain protein; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197:IPR017200:IPR006638; KEGG: sfu:Sfum_3056 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; IMG reference gene:2505283651; PFAM: Radical SAM superfamily; TIGRFAM: putative heme d1 biosynthesis radical SAM protein NirJ1; radical SAM additional 4Fe4S-binding domain. (394 aa)    
Predicted Functional Partners:
AEH44650.1
Radical SAM domain protein; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR017200:IPR007197:IPR006638; KEGG: sfu:Sfum_3058 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; IMG reference gene:2505284069; PFAM: Radical SAM superfamily; TIGRFAM: putative heme d1 biosynthesis radical SAM protein NirJ2; radical SAM additional 4Fe4S-binding domain.
  
  
 
0.919
AEH44246.1
ATPase AAA-2 domain protein; COGs: COG1219 ATP-dependent protease Clp ATPase subunit; InterPro IPR013093:IPR003593; KEGG: sfu:Sfum_3055 ATPase; PFAM: ATPase AAA-2 domain protein; SMART: AAA ATPase; SPTR: ATPase AAA-2 domain protein; IMG reference gene:2505283653; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; TIGRFAM: endopeptidase Clp ATP-binding regulatory subunit (clpX); Belongs to the ClpX chaperone family.
       0.821
aroD
3-dehydroquinate dehydratase, type I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.
       0.817
AEH44243.1
Phosphoribosylaminoimidazolecarboxamide formyltransferase; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR011607:IPR013982; KEGG: dak:DaAHT2_0500 IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region; PRIAM: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SPTR: IMP cyclohydrolase; IMG reference gene:2505283650; PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain.
       0.817
AEH44057.1
Putative transcriptional regulator, AsnC family; COGs: COG1522 Transcriptional regulators; InterPro IPR019888; KEGG: dba:Dbac_2394 putative transcriptional regulator, AsnC family; SMART: Transcription regulator AsnC-type; SPTR: Putative transcriptional regulator, AsnC family; IMG reference gene:2505283455.
 
  
 0.788
AEH44725.1
COGs: COG1522 Transcriptional regulators; InterPro IPR019888; KEGG: sfu:Sfum_4037 AsnC family transcriptional regulator; SMART: Transcription regulator AsnC-type; SPTR: Transcriptional regulator, AsnC family; IMG reference gene:2505284150.
 
  
 0.782
AEH43944.1
COGs: COG1522 Transcriptional regulators; InterPro IPR019888; KEGG: dol:Dole_2996 AsnC family transcriptional regulator; SMART: Transcription regulator AsnC-type; SPTR: Putative transcriptional regulator, AsnC family; IMG reference gene:2505283341.
  
  
 0.780
AEH44245.1
Response regulator receiver; InterPro IPR001789; KEGG: gsu:GSU0877 response regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver modulated PilZ sensor protein; IMG reference gene:2505283652; PFAM: Response regulator receiver domain.
       0.773
AEH44750.1
uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR000878:IPR003754:IPR003043:IPR006366; KEGG: dal:Dalk_4009 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; IMG reference gene:2505284177; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase.
 
  
 0.630
priA
Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
       0.573
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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