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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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AEH44245.1Response regulator receiver; InterPro IPR001789; KEGG: gsu:GSU0877 response regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver modulated PilZ sensor protein; IMG reference gene:2505283652; PFAM: Response regulator receiver domain. (121 aa)    
Predicted Functional Partners:
aroD
3-dehydroquinate dehydratase, type I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.
       0.773
AEH44243.1
Phosphoribosylaminoimidazolecarboxamide formyltransferase; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR011607:IPR013982; KEGG: dak:DaAHT2_0500 IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region; PRIAM: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SPTR: IMP cyclohydrolase; IMG reference gene:2505283650; PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain.
       0.773
AEH44244.1
Radical SAM domain protein; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197:IPR017200:IPR006638; KEGG: sfu:Sfum_3056 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; IMG reference gene:2505283651; PFAM: Radical SAM superfamily; TIGRFAM: putative heme d1 biosynthesis radical SAM protein NirJ1; radical SAM additional 4Fe4S-binding domain.
       0.773
AEH44246.1
ATPase AAA-2 domain protein; COGs: COG1219 ATP-dependent protease Clp ATPase subunit; InterPro IPR013093:IPR003593; KEGG: sfu:Sfum_3055 ATPase; PFAM: ATPase AAA-2 domain protein; SMART: AAA ATPase; SPTR: ATPase AAA-2 domain protein; IMG reference gene:2505283653; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; TIGRFAM: endopeptidase Clp ATP-binding regulatory subunit (clpX); Belongs to the ClpX chaperone family.
       0.773
AEH44948.1
Response regulator receiver sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR020053:IPR001789:IPR003661:IPR003594:IPR 004358:IPR005467; KEGG: cts:Ctha_2310 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SPTR: Putative Histidine kinase; IMG reference gene:2505284387; PFAM: Histidine [...]
 
 
 0.708
AEH44943.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR003594:IPR001789:IPR004358:IPR 013767:IPR005467; KEGG: ddf:DEFDS_0784 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; response regulator receiver; SPTR: Putative uncharacterized protein; TIGRFAM: PAS sensor protein; IMG reference gene:2505284382; PFAM: Histidine kinase-, DNA gy [...]
 
 
 0.684
AEH45062.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003661:IPR003594:IPR 001789:IPR004358:IPR013656:IPR013767:IPR005467:IPR000700; KEGG: ppd:Ppro_0904 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; PAC repeat-containing protein; histidine kinase A domain protein; response regulator r [...]
 
 
 0.658
AEH45183.1
COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160:IPR001789; KEGG: dak:DaAHT2_1538 response regulator receiver modulated diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; SMART: GGDEF domain containing protein; response regulator receiver; SPTR: Response regulator receiver modulated diguanylate cyclase; TIGRFAM: diguanylate cyclase; IMG reference gene:2505284630; PFAM: Response regulator receiver domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
  
 0.594
AEH45521.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR003594:IPR001789:IPR005467; KEGG: cau:Caur_1383 PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; response regulator receiver; SPTR: PAS sensor protein; IMG reference gene:2505284984; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain.
 
 
 0.592
AEH44846.1
Diguanylate cyclase/phosphodiesterase with GAF sensor; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR000160:IPR001633:IPR003018; KEGG: rfr:Rfer_1825 response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain protein; GGDEF domain containing protein; GAF domain protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S); TIGRFAM: diguanylate cyclase; IMG [...]
 
  
 0.590
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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