Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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AEH44248.1Hydrolase, TatD family; COGs: COG0084 Mg-dependent DNase; InterPro IPR015991:IPR001130:IPR012278:IPR018228; KEGG: sat:SYN_03204 sec-independent protein translocase protein; PFAM: TatD-related deoxyribonuclease; SPTR: Sec-independent protein translocase protein; TIGRFAM: hydrolase, TatD family; IMG reference gene:2505283655; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family. (255 aa)    
Predicted Functional Partners:
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
 0.883
AEH44249.1
Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
       0.799
AEH44250.1
Protein TolR; COGs: COG0848 Biopolymer transport protein; InterPro IPR014168:IPR003400; KEGG: tye:THEYE_A0958 TolR protein; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: TolR protein; TIGRFAM: protein TolR; IMG reference gene:2505283657; PFAM: Biopolymer transport protein ExbD/TolR; TIGRFAM: TolR protein.
       0.782
AEH44251.1
TonB family protein; InterPro IPR006260; KEGG: abo:ABO_0757 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: TonB family protein; IMG reference gene:2505283658; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain.
       0.779
AEH44252.1
TolB domain-containing protein; COGs: COG0823 Periplasmic component of the Tol biopolymer transport system; InterPro IPR011659:IPR014167; KEGG: sfu:Sfum_0755 TolB domain-containing protein; SPTR: TolB, N-terminal domain protein; IMG reference gene:2505283659; PFAM: WD40-like Beta Propeller Repeat; TolB amino-terminal domain; TIGRFAM: tol-pal system beta propeller repeat protein TolB.
       0.775
secF
Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
  
  
 0.597
rsmA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
  
 0.547
priA
Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
       0.545
AEH44243.1
Phosphoribosylaminoimidazolecarboxamide formyltransferase; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR011607:IPR013982; KEGG: dak:DaAHT2_0500 IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region; PRIAM: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SPTR: IMP cyclohydrolase; IMG reference gene:2505283650; PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain.
   
   0.455
AEH44257.1
3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.449
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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