Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
AEH44250.1Protein TolR; COGs: COG0848 Biopolymer transport protein; InterPro IPR014168:IPR003400; KEGG: tye:THEYE_A0958 TolR protein; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: TolR protein; TIGRFAM: protein TolR; IMG reference gene:2505283657; PFAM: Biopolymer transport protein ExbD/TolR; TIGRFAM: TolR protein. (133 aa)    
Predicted Functional Partners:
AEH45154.1
MotA/TolQ/ExbB proton channel; COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: dat:HRM2_30590 TolQ1; PFAM: MotA/TolQ/ExbB proton channel; SPTR: TolQ1; IMG reference gene:2505284601; PFAM: MotA/TolQ/ExbB proton channel family.
 
 
 0.969
AEH44251.1
TonB family protein; InterPro IPR006260; KEGG: abo:ABO_0757 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: TonB family protein; IMG reference gene:2505283658; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain.
  
 
 0.959
AEH45849.1
MotA/TolQ/ExbB proton channel; COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: min:Minf_0249 MotA/TolQ/ExbB proton channel family protein; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel family protein; IMG reference gene:2505285332; PFAM: MotA/TolQ/ExbB proton channel family.
 
 
 0.941
AEH44252.1
TolB domain-containing protein; COGs: COG0823 Periplasmic component of the Tol biopolymer transport system; InterPro IPR011659:IPR014167; KEGG: sfu:Sfum_0755 TolB domain-containing protein; SPTR: TolB, N-terminal domain protein; IMG reference gene:2505283659; PFAM: WD40-like Beta Propeller Repeat; TolB amino-terminal domain; TIGRFAM: tol-pal system beta propeller repeat protein TolB.
 
  
 0.916
AEH45847.1
COGs: COG0810 Periplasmic protein TonB links inner and outer membranes; InterPro IPR006260; KEGG: hth:HTH_1676 TonB family protein; PFAM: TonB domain; SPTR: TonB family protein; TIGRFAM: TonB family protein; IMG reference gene:2505285330; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain.
  
 
 0.827
AEH44249.1
Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
   
 
 0.800
AEH44248.1
Hydrolase, TatD family; COGs: COG0084 Mg-dependent DNase; InterPro IPR015991:IPR001130:IPR012278:IPR018228; KEGG: sat:SYN_03204 sec-independent protein translocase protein; PFAM: TatD-related deoxyribonuclease; SPTR: Sec-independent protein translocase protein; TIGRFAM: hydrolase, TatD family; IMG reference gene:2505283655; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family.
       0.782
pal
Peptidoglycan-associated lipoprotein; COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006664:IPR006665:IPR014169; KEGG: gme:Gmet_3541 OmpA/MotB; PFAM: OmpA/MotB domain protein; SPTR: OmpA/MotB; TIGRFAM: peptidoglycan-associated lipoprotein; IMG reference gene:2505283371; PFAM: OmpA family; TIGRFAM: peptidoglycan-associated lipoprotein; Belongs to the Pal lipoprotein family.
 
 
 
 0.726
AEH44484.1
COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR016474:IPR010827:IPR000184; KEGG: dak:DaAHT2_1309 outer membrane protein assembly complex, YaeT protein; PFAM: surface antigen (D15); surface antigen variable number repeat-containing protein; SPTR: Surface antigen (D15):Surface antigen variable number; TIGRFAM: outer membrane protein assembly complex, YaeT protein; IMG reference gene:2505283898; PFAM: Surface antigen variable number repeat; Surface antigen; TIGRFAM: outer membrane protein assembly complex, YaeT protein.
  
   
 0.628
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
   
 
 0.563
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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