Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
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gene co-occurrence
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AEH44279.1COGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783; KEGG: dol:Dole_2078 riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; PRIAM: Riboflavin synthase; SPTR: Riboflavin synthase, alpha subunit; TIGRFAM: riboflavin synthase, alpha subunit; IMG reference gene:2505283686; PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit. (215 aa)    
Predicted Functional Partners:
AEH44458.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
 0.999
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
 
 0.999
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 0.999
AEH44937.1
Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR015864:IPR015865:IPR002606; KEGG: dak:DaAHT2_1659 riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; SPTR: Riboflavin kinase / FAD synthetase; TIGRFAM: riboflavin biosynthesis protein RibF; IMG reference gene:2505284376; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family.
    
 0.934
AEH44280.1
Chromosome segregation and condensation protein, ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
       0.799
AEH44281.1
KEGG: dak:DaAHT2_0853 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505283688.
       0.782
AEH44282.1
KEGG: dak:DaAHT2_1271 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505283689.
       0.767
AEH44277.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR004358:IPR005467; KEGG: drt:Dret_0468 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensory box histidine kinase PhoR; IMG reference gene:2505283684; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
       0.569
AEH44278.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: gme:Gmet_2693 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; IMG reference gene:2505283685; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
       0.569
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.450
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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