| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEH43901.1 | AEH44327.1 | Thein_0015 | Thein_0445 | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: chy:CHY_1057 hypothetical protein; PFAM: NAD-dependent epimerase/dehydratase; SPTR: Conserved domain protein; IMG reference gene:2505283296; PFAM: NAD dependent epimerase/dehydratase family. | UDP-N-acetylglucosamine 4,6-dehydratase; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR020025:IPR003869; KEGG: hth:HTH_1539 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein CapD; SPTR: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase; IMG reference gene:2505283734; PFAM: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase. | 0.917 |
| AEH43901.1 | AEH44764.1 | Thein_0015 | Thein_0887 | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: chy:CHY_1057 hypothetical protein; PFAM: NAD-dependent epimerase/dehydratase; SPTR: Conserved domain protein; IMG reference gene:2505283296; PFAM: NAD dependent epimerase/dehydratase family. | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR005835:IPR001538:IPR006375; KEGG: saf:SULAZ_0358 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; PRIAM: Mannose-6-phosphate isomerase; SPTR: Strongly similar to GDP-mannose pyrophosphorylase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; IMG reference gene:2505284191; PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomera [...] | 0.552 |
| AEH43901.1 | AEH45203.1 | Thein_0015 | Thein_1336 | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: chy:CHY_1057 hypothetical protein; PFAM: NAD-dependent epimerase/dehydratase; SPTR: Conserved domain protein; IMG reference gene:2505283296; PFAM: NAD dependent epimerase/dehydratase family. | COGs: COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); InterPro IPR005835; KEGG: dae:Dtox_0205 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; PFAM: Nucleotidyl transferase; PRIAM: Glucosamine-1-phosphate N-acetyltransferase; SPTR: Bifunctional protein glmU; IMG reference gene:2505284650; PFAM: Nucleotidyl transferase; TIGRFAM: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase. | 0.903 |
| AEH43901.1 | AEH45380.1 | Thein_0015 | Thein_1519 | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: chy:CHY_1057 hypothetical protein; PFAM: NAD-dependent epimerase/dehydratase; SPTR: Conserved domain protein; IMG reference gene:2505283296; PFAM: NAD dependent epimerase/dehydratase family. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.818 |
| AEH43901.1 | murA | Thein_0015 | Thein_0588 | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: chy:CHY_1057 hypothetical protein; PFAM: NAD-dependent epimerase/dehydratase; SPTR: Conserved domain protein; IMG reference gene:2505283296; PFAM: NAD dependent epimerase/dehydratase family. | UDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.904 |
| AEH44326.1 | AEH44327.1 | Thein_0444 | Thein_0445 | KEGG: tet:TTHERM_01193540 Protein kinase domain containing protein; SPTR: Protein kinase domain containing protein; IMG reference gene:2505283733. | UDP-N-acetylglucosamine 4,6-dehydratase; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR020025:IPR003869; KEGG: hth:HTH_1539 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein CapD; SPTR: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase; IMG reference gene:2505283734; PFAM: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase. | 0.773 |
| AEH44326.1 | AEH44328.1 | Thein_0444 | Thein_0446 | KEGG: tet:TTHERM_01193540 Protein kinase domain containing protein; SPTR: Protein kinase domain containing protein; IMG reference gene:2505283733. | UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR020026:IPR000653; KEGG: msi:Msm_1536 pleiotropic regulatory protein DegT (PLP-dependent); PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: DegT/DnrJ/EryC1/StrS aminotransferase; TIGRFAM: UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; IMG reference gene:2505283735; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; TIGRFAM: UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; Belongs to t [...] | 0.773 |
| AEH44326.1 | AEH44329.1 | Thein_0444 | Thein_0447 | KEGG: tet:TTHERM_01193540 Protein kinase domain containing protein; SPTR: Protein kinase domain containing protein; IMG reference gene:2505283733. | Acylneuraminate cytidylyltransferase; COGs: COG1861 Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase homolog; InterPro IPR003329; KEGG: msi:Msm_1537 acylneuraminate cytidylyltransferase NeuS; PFAM: acylneuraminate cytidylyltransferase; SPTR: Predicted acylneuraminate cytidylyltransferase, NeuS; IMG reference gene:2505283736; PFAM: Cytidylyltransferase. | 0.773 |
| AEH44326.1 | AEH44330.1 | Thein_0444 | Thein_0448 | KEGG: tet:TTHERM_01193540 Protein kinase domain containing protein; SPTR: Protein kinase domain containing protein; IMG reference gene:2505283733. | Pseudaminic acid biosynthesis-associated protein PseG; COGs: COG3980 Spore coat polysaccharide biosynthesis protein predicted glycosyltransferase; InterPro IPR020023:IPR007235:IPR000182; KEGG: msi:Msm_1538 CMP-sialic acid synthetase, NeuA; PFAM: GCN5-related N-acetyltransferase; Glycosyltransferase 28 domain; SPTR: CMP-sialic acid synthetase, NeuA; TIGRFAM: pseudaminic acid biosynthesis-associated protein PseG; IMG reference gene:2505283737; PFAM: Acetyltransferase (GNAT) family; Glycosyltransferase family 28 C-terminal domain; TIGRFAM: pseudaminic acid biosynthesis-associated protein PseG. | 0.773 |
| AEH44326.1 | AEH44331.1 | Thein_0444 | Thein_0449 | KEGG: tet:TTHERM_01193540 Protein kinase domain containing protein; SPTR: Protein kinase domain containing protein; IMG reference gene:2505283733. | COGs: COG2089 Sialic acid synthase; InterPro IPR020030:IPR013132:IPR013974:IPR006190; KEGG: tmt:Tmath_0718 pseudaminic acid synthase; PFAM: N-acetylneuraminic acid synthase domain; SAF domain protein; PRIAM: N-acetylneuraminate synthase; SPTR: Sialic acid synthase; TIGRFAM: pseudaminic acid synthase; IMG reference gene:2505283738; PFAM: SAF domain; NeuB family; TIGRFAM: pseudaminic acid synthase. | 0.773 |
| AEH44327.1 | AEH43901.1 | Thein_0445 | Thein_0015 | UDP-N-acetylglucosamine 4,6-dehydratase; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR020025:IPR003869; KEGG: hth:HTH_1539 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein CapD; SPTR: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase; IMG reference gene:2505283734; PFAM: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase. | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: chy:CHY_1057 hypothetical protein; PFAM: NAD-dependent epimerase/dehydratase; SPTR: Conserved domain protein; IMG reference gene:2505283296; PFAM: NAD dependent epimerase/dehydratase family. | 0.917 |
| AEH44327.1 | AEH44326.1 | Thein_0445 | Thein_0444 | UDP-N-acetylglucosamine 4,6-dehydratase; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR020025:IPR003869; KEGG: hth:HTH_1539 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein CapD; SPTR: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase; IMG reference gene:2505283734; PFAM: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase. | KEGG: tet:TTHERM_01193540 Protein kinase domain containing protein; SPTR: Protein kinase domain containing protein; IMG reference gene:2505283733. | 0.773 |
| AEH44327.1 | AEH44328.1 | Thein_0445 | Thein_0446 | UDP-N-acetylglucosamine 4,6-dehydratase; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR020025:IPR003869; KEGG: hth:HTH_1539 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein CapD; SPTR: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase; IMG reference gene:2505283734; PFAM: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase. | UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR020026:IPR000653; KEGG: msi:Msm_1536 pleiotropic regulatory protein DegT (PLP-dependent); PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: DegT/DnrJ/EryC1/StrS aminotransferase; TIGRFAM: UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; IMG reference gene:2505283735; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; TIGRFAM: UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; Belongs to t [...] | 0.997 |
| AEH44327.1 | AEH44329.1 | Thein_0445 | Thein_0447 | UDP-N-acetylglucosamine 4,6-dehydratase; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR020025:IPR003869; KEGG: hth:HTH_1539 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein CapD; SPTR: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase; IMG reference gene:2505283734; PFAM: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase. | Acylneuraminate cytidylyltransferase; COGs: COG1861 Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase homolog; InterPro IPR003329; KEGG: msi:Msm_1537 acylneuraminate cytidylyltransferase NeuS; PFAM: acylneuraminate cytidylyltransferase; SPTR: Predicted acylneuraminate cytidylyltransferase, NeuS; IMG reference gene:2505283736; PFAM: Cytidylyltransferase. | 0.935 |
| AEH44327.1 | AEH44330.1 | Thein_0445 | Thein_0448 | UDP-N-acetylglucosamine 4,6-dehydratase; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR020025:IPR003869; KEGG: hth:HTH_1539 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein CapD; SPTR: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase; IMG reference gene:2505283734; PFAM: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase. | Pseudaminic acid biosynthesis-associated protein PseG; COGs: COG3980 Spore coat polysaccharide biosynthesis protein predicted glycosyltransferase; InterPro IPR020023:IPR007235:IPR000182; KEGG: msi:Msm_1538 CMP-sialic acid synthetase, NeuA; PFAM: GCN5-related N-acetyltransferase; Glycosyltransferase 28 domain; SPTR: CMP-sialic acid synthetase, NeuA; TIGRFAM: pseudaminic acid biosynthesis-associated protein PseG; IMG reference gene:2505283737; PFAM: Acetyltransferase (GNAT) family; Glycosyltransferase family 28 C-terminal domain; TIGRFAM: pseudaminic acid biosynthesis-associated protein PseG. | 0.972 |
| AEH44327.1 | AEH44331.1 | Thein_0445 | Thein_0449 | UDP-N-acetylglucosamine 4,6-dehydratase; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR020025:IPR003869; KEGG: hth:HTH_1539 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein CapD; SPTR: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase; IMG reference gene:2505283734; PFAM: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase. | COGs: COG2089 Sialic acid synthase; InterPro IPR020030:IPR013132:IPR013974:IPR006190; KEGG: tmt:Tmath_0718 pseudaminic acid synthase; PFAM: N-acetylneuraminic acid synthase domain; SAF domain protein; PRIAM: N-acetylneuraminate synthase; SPTR: Sialic acid synthase; TIGRFAM: pseudaminic acid synthase; IMG reference gene:2505283738; PFAM: SAF domain; NeuB family; TIGRFAM: pseudaminic acid synthase. | 0.936 |
| AEH44327.1 | AEH44764.1 | Thein_0445 | Thein_0887 | UDP-N-acetylglucosamine 4,6-dehydratase; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR020025:IPR003869; KEGG: hth:HTH_1539 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein CapD; SPTR: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase; IMG reference gene:2505283734; PFAM: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase. | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR005835:IPR001538:IPR006375; KEGG: saf:SULAZ_0358 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; PRIAM: Mannose-6-phosphate isomerase; SPTR: Strongly similar to GDP-mannose pyrophosphorylase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; IMG reference gene:2505284191; PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomera [...] | 0.845 |
| AEH44327.1 | AEH45203.1 | Thein_0445 | Thein_1336 | UDP-N-acetylglucosamine 4,6-dehydratase; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR020025:IPR003869; KEGG: hth:HTH_1539 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein CapD; SPTR: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase; IMG reference gene:2505283734; PFAM: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase. | COGs: COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); InterPro IPR005835; KEGG: dae:Dtox_0205 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; PFAM: Nucleotidyl transferase; PRIAM: Glucosamine-1-phosphate N-acetyltransferase; SPTR: Bifunctional protein glmU; IMG reference gene:2505284650; PFAM: Nucleotidyl transferase; TIGRFAM: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase. | 0.907 |
| AEH44327.1 | AEH45380.1 | Thein_0445 | Thein_1519 | UDP-N-acetylglucosamine 4,6-dehydratase; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR020025:IPR003869; KEGG: hth:HTH_1539 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein CapD; SPTR: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase; IMG reference gene:2505283734; PFAM: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.806 |
| AEH44327.1 | murA | Thein_0445 | Thein_0588 | UDP-N-acetylglucosamine 4,6-dehydratase; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR020025:IPR003869; KEGG: hth:HTH_1539 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein CapD; SPTR: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase; IMG reference gene:2505283734; PFAM: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase. | UDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.905 |