close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44327.1UDP-N-acetylglucosamine 4,6-dehydratase; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR020025:IPR003869; KEGG: hth:HTH_1539 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein CapD; SPTR: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase; IMG reference gene:2505283734; PFAM: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase. (332 aa)    
Predicted Functional Partners:
AEH44328.1
UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR020026:IPR000653; KEGG: msi:Msm_1536 pleiotropic regulatory protein DegT (PLP-dependent); PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: DegT/DnrJ/EryC1/StrS aminotransferase; TIGRFAM: UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; IMG reference gene:2505283735; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; TIGRFAM: UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; Belongs to t [...]
 
 
 0.997
AEH44330.1
Pseudaminic acid biosynthesis-associated protein PseG; COGs: COG3980 Spore coat polysaccharide biosynthesis protein predicted glycosyltransferase; InterPro IPR020023:IPR007235:IPR000182; KEGG: msi:Msm_1538 CMP-sialic acid synthetase, NeuA; PFAM: GCN5-related N-acetyltransferase; Glycosyltransferase 28 domain; SPTR: CMP-sialic acid synthetase, NeuA; TIGRFAM: pseudaminic acid biosynthesis-associated protein PseG; IMG reference gene:2505283737; PFAM: Acetyltransferase (GNAT) family; Glycosyltransferase family 28 C-terminal domain; TIGRFAM: pseudaminic acid biosynthesis-associated protein PseG.
 
   
 0.972
AEH44331.1
COGs: COG2089 Sialic acid synthase; InterPro IPR020030:IPR013132:IPR013974:IPR006190; KEGG: tmt:Tmath_0718 pseudaminic acid synthase; PFAM: N-acetylneuraminic acid synthase domain; SAF domain protein; PRIAM: N-acetylneuraminate synthase; SPTR: Sialic acid synthase; TIGRFAM: pseudaminic acid synthase; IMG reference gene:2505283738; PFAM: SAF domain; NeuB family; TIGRFAM: pseudaminic acid synthase.
 
  
 0.936
AEH44329.1
Acylneuraminate cytidylyltransferase; COGs: COG1861 Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase homolog; InterPro IPR003329; KEGG: msi:Msm_1537 acylneuraminate cytidylyltransferase NeuS; PFAM: acylneuraminate cytidylyltransferase; SPTR: Predicted acylneuraminate cytidylyltransferase, NeuS; IMG reference gene:2505283736; PFAM: Cytidylyltransferase.
 
   
 0.935
AEH43901.1
NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: chy:CHY_1057 hypothetical protein; PFAM: NAD-dependent epimerase/dehydratase; SPTR: Conserved domain protein; IMG reference gene:2505283296; PFAM: NAD dependent epimerase/dehydratase family.
 
 
0.917
AEH45203.1
COGs: COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); InterPro IPR005835; KEGG: dae:Dtox_0205 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; PFAM: Nucleotidyl transferase; PRIAM: Glucosamine-1-phosphate N-acetyltransferase; SPTR: Bifunctional protein glmU; IMG reference gene:2505284650; PFAM: Nucleotidyl transferase; TIGRFAM: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase.
    
 0.907
murA
UDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
    
 0.905
AEH44764.1
Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR005835:IPR001538:IPR006375; KEGG: saf:SULAZ_0358 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; PRIAM: Mannose-6-phosphate isomerase; SPTR: Strongly similar to GDP-mannose pyrophosphorylase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; IMG reference gene:2505284191; PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomera [...]
  
  
 0.845
AEH45380.1
acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
    
  0.806
AEH44326.1
KEGG: tet:TTHERM_01193540 Protein kinase domain containing protein; SPTR: Protein kinase domain containing protein; IMG reference gene:2505283733.
       0.773
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: low (32%) [HD]