close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44331.1COGs: COG2089 Sialic acid synthase; InterPro IPR020030:IPR013132:IPR013974:IPR006190; KEGG: tmt:Tmath_0718 pseudaminic acid synthase; PFAM: N-acetylneuraminic acid synthase domain; SAF domain protein; PRIAM: N-acetylneuraminate synthase; SPTR: Sialic acid synthase; TIGRFAM: pseudaminic acid synthase; IMG reference gene:2505283738; PFAM: SAF domain; NeuB family; TIGRFAM: pseudaminic acid synthase. (350 aa)    
Predicted Functional Partners:
AEH44330.1
Pseudaminic acid biosynthesis-associated protein PseG; COGs: COG3980 Spore coat polysaccharide biosynthesis protein predicted glycosyltransferase; InterPro IPR020023:IPR007235:IPR000182; KEGG: msi:Msm_1538 CMP-sialic acid synthetase, NeuA; PFAM: GCN5-related N-acetyltransferase; Glycosyltransferase 28 domain; SPTR: CMP-sialic acid synthetase, NeuA; TIGRFAM: pseudaminic acid biosynthesis-associated protein PseG; IMG reference gene:2505283737; PFAM: Acetyltransferase (GNAT) family; Glycosyltransferase family 28 C-terminal domain; TIGRFAM: pseudaminic acid biosynthesis-associated protein PseG.
 
 
 0.998
AEH44616.1
N-acylneuraminate cytidylyltransferase; COGs: COG1083 CMP-N-acetylneuraminic acid synthetase; InterPro IPR003329; KEGG: mru:mru_1876 CMP-N-acetylneuraminic acid synthetase NeuA; PFAM: acylneuraminate cytidylyltransferase; PRIAM: N-acylneuraminate cytidylyltransferase; SPTR: CMP-N-acetylneuraminic acid synthetase NeuA; IMG reference gene:2505284033; PFAM: Cytidylyltransferase; Glycosyltransferase family 28 C-terminal domain.
  
 0.968
AEH44329.1
Acylneuraminate cytidylyltransferase; COGs: COG1861 Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase homolog; InterPro IPR003329; KEGG: msi:Msm_1537 acylneuraminate cytidylyltransferase NeuS; PFAM: acylneuraminate cytidylyltransferase; SPTR: Predicted acylneuraminate cytidylyltransferase, NeuS; IMG reference gene:2505283736; PFAM: Cytidylyltransferase.
 
  
 0.964
AEH44327.1
UDP-N-acetylglucosamine 4,6-dehydratase; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR020025:IPR003869; KEGG: hth:HTH_1539 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein CapD; SPTR: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase; IMG reference gene:2505283734; PFAM: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase.
 
  
 0.936
AEH44328.1
UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR020026:IPR000653; KEGG: msi:Msm_1536 pleiotropic regulatory protein DegT (PLP-dependent); PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: DegT/DnrJ/EryC1/StrS aminotransferase; TIGRFAM: UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; IMG reference gene:2505283735; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; TIGRFAM: UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; Belongs to t [...]
 
  
 0.877
AEH44326.1
KEGG: tet:TTHERM_01193540 Protein kinase domain containing protein; SPTR: Protein kinase domain containing protein; IMG reference gene:2505283733.
       0.773
AEH44332.1
Protein of unknown function DUF115; COGs: COG2604 conserved hypothetical protein; InterPro IPR002826; KEGG: hth:HTH_0655 hypothetical protein; PFAM: protein of unknown function DUF115; SPTR: Putative uncharacterized protein; IMG reference gene:2505283739; PFAM: Alpha-2,3-sialyltransferase (CST-I); Protein of unknown function DUF115.
 
  
 0.640
AEH44593.1
Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362:IPR017472:IPR017475; KEGG: hya:HY04AAS1_0831 undecaprenyl-phosphate galactose phosphotransferase, WbaP; PFAM: sugar transferase; PRIAM: Undecaprenyl-phosphate galactose phosphotransferase; SPTR: Undecaprenyl-phosphate galactosephosphotransferase; TIGRFAM: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Undecaprenyl-phosphate galactose phosphotransferase, WbaP; IMG reference gene:2505284010; PFAM: Bacteri [...]
  
  
 0.567
AEH45264.1
3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; COGs: COG1778 Low specificity phosphatase (HAD superfamily); InterPro IPR010023:IPR006549; KEGG: sfu:Sfum_2073 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; PRIAM: 3-deoxy-manno-octulosonate-8-phosphatase; SPTR: Phosphatase kdsC; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; hydrolase, HAD-superfamily, subfamily IIIA; IMG reference gene:2505284713; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family.
   
 0.471
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.