Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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csrACarbon storage regulator, CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. (76 aa)    
Predicted Functional Partners:
fliW
Protein of unknown function DUF180; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
 
 
 0.996
AEH44339.1
COGs: COG1344 Flagellin and related hook-associated protein; InterPro IPR013384:IPR001492; KEGG: mta:Moth_0747 flagellar hook-associated protein FlgL; PFAM: flagellin domain protein; SPTR: Flagellin-like; TIGRFAM: flagellar hook-associated protein 3; IMG reference gene:2505283746; PFAM: Bacterial flagellin N-terminal helical region; Bacterial flagellin C-terminal helical region; TIGRFAM: flagellar hook-associated protein 3.
 
  
 0.908
AEH44340.1
COGs: COG1256 Flagellar hook-associated protein; InterPro IPR002371:IPR010930:IPR018247; KEGG: dde:Dde_3152 flagellar hook-associated protein; PFAM: protein of unknown function DUF1078 domain protein; SPTR: Putative uncharacterized protein; TIGRFAM: flagellar hook-associated protein FlgK; IMG reference gene:2505283747; PFAM: Domain of unknown function (DUF1078); TIGRFAM: flagellar hook-associated protein FlgK.
  
  
 0.866
flgI
Flagellar P-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
     
 0.772
AEH44346.1
Flagella basal body P-ring formation protein FlgA; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.
     
 0.768
flgH
Flagellar L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
     
 0.765
AEH44343.1
Flagellar protein FlgJ; InterPro IPR019301; KEGG: csc:Csac_0596 hypothetical protein; PFAM: Flagellar protein FlgJ-like; SPTR: Putative uncharacterized protein; IMG reference gene:2505283750; PFAM: Rod binding protein.
       0.762
AEH44341.1
FlgN family protein; InterPro IPR007809; KEGG: rde:RD1_0161 hypothetical protein; PFAM: FlgN family protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505283748; PFAM: FlgN protein.
       0.737
AEH44342.1
Hypothetical protein; IMG reference gene:2505283749.
       0.731
AEH44336.1
Flagellar hook-associated 2 domain-containing protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
  
  
 0.708
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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