Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEH44339.1COGs: COG1344 Flagellin and related hook-associated protein; InterPro IPR013384:IPR001492; KEGG: mta:Moth_0747 flagellar hook-associated protein FlgL; PFAM: flagellin domain protein; SPTR: Flagellin-like; TIGRFAM: flagellar hook-associated protein 3; IMG reference gene:2505283746; PFAM: Bacterial flagellin N-terminal helical region; Bacterial flagellin C-terminal helical region; TIGRFAM: flagellar hook-associated protein 3. (316 aa)    
Predicted Functional Partners:
AEH44340.1
COGs: COG1256 Flagellar hook-associated protein; InterPro IPR002371:IPR010930:IPR018247; KEGG: dde:Dde_3152 flagellar hook-associated protein; PFAM: protein of unknown function DUF1078 domain protein; SPTR: Putative uncharacterized protein; TIGRFAM: flagellar hook-associated protein FlgK; IMG reference gene:2505283747; PFAM: Domain of unknown function (DUF1078); TIGRFAM: flagellar hook-associated protein FlgK.
 
 
 0.995
AEH44336.1
Flagellar hook-associated 2 domain-containing protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
 
 
 0.975
AEH44335.1
Flagellar protein FliS; COGs: COG1516 Flagellin-specific chaperone FliS; InterPro IPR003713; KEGG: dak:DaAHT2_0290 flagellar protein FliS; PFAM: flagellar protein FliS; SPTR: Flagellar protein FliS; IMG reference gene:2505283742; PFAM: Flagellar protein FliS; TIGRFAM: flagellar biosynthetic protein FliS.
 
 
 0.963
fliW
Protein of unknown function DUF180; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
 
 
 0.950
AEH44343.1
Flagellar protein FlgJ; InterPro IPR019301; KEGG: csc:Csac_0596 hypothetical protein; PFAM: Flagellar protein FlgJ-like; SPTR: Putative uncharacterized protein; IMG reference gene:2505283750; PFAM: Rod binding protein.
 
  
 0.922
AEH44348.1
COGs: COG4786 Flagellar basal body rod protein; InterPro IPR020013:IPR012836:IPR001444; KEGG: geo:Geob_0627 flagellar basal-body rod protein FlgF; PFAM: flagellar basal body rod protein; SPTR: Flagellar basal-body rod protein FlgF; TIGRFAM: flagellar basal-body rod protein FlgF; fagellar hook-basal body protein; IMG reference gene:2505283755; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: flagellar basal-body rod protein FlgF; fagellar hook-basal body proteins.
 
 
 0.916
AEH45664.1
Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
 
 
 0.915
csrA
Carbon storage regulator, CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
 
  
 0.908
flgH
Flagellar L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
  
 
 0.906
AEH44347.1
COGs: COG4786 Flagellar basal body rod protein; InterProIPR020013:IPR012834:IPR001444:IPR010930:IPR 019776; KEGG: dal:Dalk_0993 flagellar basal body rod protein FlgG; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; SPTR: Flagellar basal-body rod protein FlgG; TIGRFAM: flagellar basal-body rod protein FlgG; fagellar hook-basal body protein; IMG reference gene:2505283754; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: flagellar basal-body rod protein FlgF; fagellar hook-basal body proteins; flagellar basal [...]
 
 
 0.906
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.