Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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AEH44364.1Transketolase domain-containing protein; COGs: COG0021 Transketolase; InterPro IPR005474:IPR005475:IPR005476; KEGG: sfu:Sfum_1302 transketolase; PFAM: Transketolase domain-containing protein; Transketolase central region; SPTR: Transketolase domain protein; IMG reference gene:2505283771; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. (647 aa)    
Predicted Functional Partners:
AEH44437.1
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
 
 0.997
AEH44198.1
COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: dak:DaAHT2_1975 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Ribulose-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; IMG reference gene:2505283603; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase.
 0.990
AEH43934.1
Phosphoglucose isomerase (PGI); COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001672; KEGG: srm:SRM_00085 putative transaldolase phosphoglucose isomerase; PFAM: phosphoglucose isomerase (PGI); SPTR: Putative Transaldolase Phosphoglucose isomerase; IMG reference gene:2505283331; PFAM: Phosphoglucose isomerase; Belongs to the GPI family.
 0.974
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.974
AEH45420.1
Ketose-bisphosphate aldolase class-II; InterPro IPR019825:IPR000771; KEGG: tye:THEYE_A1945 hypothetical protein; PFAM: ketose-bisphosphate aldolase class-II; SPTR: Putative uncharacterized protein; IMG reference gene:2505284878; PFAM: Fructose-bisphosphate aldolase class-II.
  
 0.968
AEH45276.1
COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterPro IPR020828:IPR020829:IPR020830:IPR020832; KEGG: dol:Dole_0222 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: Glyceraldehyde-3-phosphate dehydrogenase (Phosphorylating); manually curated; IMG reference gene:2505284725; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-termina [...]
 
 0.963
AEH45274.1
COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterProIPR006424:IPR020828:IPR020829:IPR020830:IPR 010916:IPR020832:IPR020831; KEGG: dak:DaAHT2_2095 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: Glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; IMG reference gene:2505284723; PFAM [...]
  
 0.954
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 0.952
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 
 0.951
AEH44262.1
Sugar-phosphate isomerase, RpiB/LacA/LacB family; COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR004785:IPR003500; KEGG: tal:Thal_0562 ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase; PRIAM: Galactose-6-phosphate isomerase; SPTR: Ribose 5-phosphate isomerase B; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; IMG reference gene:2505283669; PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerases, RpiB/LacA/LacB family.
  
 
 0.936
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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