Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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gene co-occurrence
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AEH44375.1Biotin and thiamin synthesis associated; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR007197:IPR010722:IPR006638; KEGG: adg:Adeg_1241 thiamine biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Biotin and thiamin synthesis associated; IMG reference gene:2505283782; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydG; thiazole biosynthesis protein ThiH. (497 aa)    
Predicted Functional Partners:
AEH44381.1
Small GTP-binding protein; COGs: COG1160 GTPase; InterPro IPR005225:IPR002917:IPR001806:IPR003577; KEGG: pca:Pcar_1629 GTPases; PFAM: GTP-binding protein HSR1-related; SMART: Ras small GTPase, Ras type; SPTR: Predicted GTPases; TIGRFAM: small GTP-binding protein; IMG reference gene:2505283788; PFAM: GTPase of unknown function; TIGRFAM: hydrogenase maturation GTPase HydF; small GTP-binding protein domain.
   
 0.943
AEH44376.1
KEGG: ate:Athe_0168 putative transcriptional regulator, CopG family; SPTR: Putative uncharacterized protein; IMG reference gene:2505283783; TIGRFAM: putative iron-only hydrogenase system regulator.
 
     0.874
AEH44377.1
Hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR013352:IPR004108:IPR003149:IPR017896:IPR 017900; KEGG: hor:Hore_06330 NADH dehydrogenase (ubiquinone) 75 kDa subunit; PFAM: hydrogenase large subunit domain protein; iron hydrogenase small subunit; PRIAM: Ferredoxin hydrogenase; SPTR: NADH dehydrogenase (Ubiquinone) 75 kDa subunit; TIGRFAM: hydrogenase, Fe-only; IMG reference gene:2505283784; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Iron hydrogenase small subunit; TIGRFAM: hydrogenase, Fe-only.
 
   
 0.869
AEH44380.1
COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterPro IPR004108:IPR017896:IPR017900; KEGG: tye:THEYE_A1726 hydrogenase; PFAM: hydrogenase large subunit domain protein; PRIAM: Ferredoxin hydrogenase; SPTR: Hydrogenase; IMG reference gene:2505283787; PFAM: Iron only hydrogenase large subunit, C-terminal domain; 4Fe-4S binding domain; TIGRFAM: hydrogenase, Fe-only.
 
     0.815
AEH45232.1
Hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR006311:IPR013352:IPR004108:IPR003149:IPR 006058:IPR017900:IPR017909:IPR017896; KEGG: pth:PTH_0668 iron only hydrogenase large subunit; PFAM: hydrogenase large subunit domain protein; iron hydrogenase small subunit; PRIAM: Ferredoxin hydrogenase; SPTR: Iron only hydrogenase large subunit, C-terminal domain; TIGRFAM: hydrogenase, Fe-only; IMG reference gene:2505284680; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Iron hydrogenase small subunit; TIGRFAM: hydrogenase, Fe-only.
 
     0.753
AEH44379.1
InterPro IPR003149; KEGG: she:Shewmr4_3251 iron hydrogenase, small subunit; PFAM: iron hydrogenase small subunit; SPTR: Iron hydrogenase, small subunit; IMG reference gene:2505283786; PFAM: Iron hydrogenase small subunit.
 
   
 0.717
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.674
AEH45664.1
Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
   
    0.636
AEH44373.1
Fumarate lyase; COGs: COG1027 Aspartate ammonia-lyase; InterPro IPR000362:IPR018951:IPR020557; KEGG: mta:Moth_1273 aspartate ammonia-lyase; PFAM: fumarate lyase; Fumarase C-like; SPTR: Fumarase; IMG reference gene:2505283780; PFAM: Fumarase C C-terminus; Lyase; TIGRFAM: aspartate ammonia-lyase.
       0.635
AEH44374.1
KEGG: adg:Adeg_1242 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505283781.
       0.625
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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