Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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AEH44380.1COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterPro IPR004108:IPR017896:IPR017900; KEGG: tye:THEYE_A1726 hydrogenase; PFAM: hydrogenase large subunit domain protein; PRIAM: Ferredoxin hydrogenase; SPTR: Hydrogenase; IMG reference gene:2505283787; PFAM: Iron only hydrogenase large subunit, C-terminal domain; 4Fe-4S binding domain; TIGRFAM: hydrogenase, Fe-only. (447 aa)    
Predicted Functional Partners:
AEH44379.1
InterPro IPR003149; KEGG: she:Shewmr4_3251 iron hydrogenase, small subunit; PFAM: iron hydrogenase small subunit; SPTR: Iron hydrogenase, small subunit; IMG reference gene:2505283786; PFAM: Iron hydrogenase small subunit.
 
   0.960
AEH44381.1
Small GTP-binding protein; COGs: COG1160 GTPase; InterPro IPR005225:IPR002917:IPR001806:IPR003577; KEGG: pca:Pcar_1629 GTPases; PFAM: GTP-binding protein HSR1-related; SMART: Ras small GTPase, Ras type; SPTR: Predicted GTPases; TIGRFAM: small GTP-binding protein; IMG reference gene:2505283788; PFAM: GTPase of unknown function; TIGRFAM: hydrogenase maturation GTPase HydF; small GTP-binding protein domain.
 
     0.856
AEH44382.1
Radical SAM domain protein; COGs: COG0502 Biotin synthase; InterPro IPR007197:IPR005244:IPR006638; KEGG: pth:PTH_0983 biotin synthase; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Biotin synthase and related enzymes; manually curated; IMG reference gene:2505283789; PFAM: Radical SAM superfamily; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydE.
 
  
 0.850
AEH46070.1
Hypothetical protein; InterPro IPR017900:IPR017896; KEGG: dap:Dacet_0088 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; manually curated; IMG reference gene:2505285561; TIGRFAM: ferredoxin-type protein NapF; MauM/NapG family ferredoxin-type protein.
   
 
 0.845
AEH44378.1
Hypothetical protein; COGs: COG2864 Cytochrome b subunit of formate dehydrogenase; InterPro IPR000516; KEGG: slp:Slip_1532 formate dehydrogenase, putative; SPTR: Putative formate dehydrogenase; IMG reference gene:2505283785; PFAM: Cytochrome b(N-terminal)/b6/petB; TIGRFAM: formate dehydrogenase, gamma subunit.
 
     0.831
AEH44375.1
Biotin and thiamin synthesis associated; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR007197:IPR010722:IPR006638; KEGG: adg:Adeg_1241 thiamine biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Biotin and thiamin synthesis associated; IMG reference gene:2505283782; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydG; thiazole biosynthesis protein ThiH.
 
     0.815
AEH44377.1
Hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR013352:IPR004108:IPR003149:IPR017896:IPR 017900; KEGG: hor:Hore_06330 NADH dehydrogenase (ubiquinone) 75 kDa subunit; PFAM: hydrogenase large subunit domain protein; iron hydrogenase small subunit; PRIAM: Ferredoxin hydrogenase; SPTR: NADH dehydrogenase (Ubiquinone) 75 kDa subunit; TIGRFAM: hydrogenase, Fe-only; IMG reference gene:2505283784; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Iron hydrogenase small subunit; TIGRFAM: hydrogenase, Fe-only.
 
 
 
0.714
AEH44376.1
KEGG: ate:Athe_0168 putative transcriptional regulator, CopG family; SPTR: Putative uncharacterized protein; IMG reference gene:2505283783; TIGRFAM: putative iron-only hydrogenase system regulator.
 
     0.634
AEH46025.1
Formate dehydrogenase, alpha subunit; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR000759:IPR001041:IPR013027:IPR006963:IPR 006656:IPR006657:IPR018247:IPR017900:IPR006655:IPR017896:I PR006478; KEGG: dak:DaAHT2_0823 formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; ferredoxin; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; SPTR: Formate dehydrogenase, alpha subunit; TIGRFAM: formate dehydrogenase, alpha subunit; manually curated; selenocysteine- [...]
   
 
 0.411
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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