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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH44381.1Small GTP-binding protein; COGs: COG1160 GTPase; InterPro IPR005225:IPR002917:IPR001806:IPR003577; KEGG: pca:Pcar_1629 GTPases; PFAM: GTP-binding protein HSR1-related; SMART: Ras small GTPase, Ras type; SPTR: Predicted GTPases; TIGRFAM: small GTP-binding protein; IMG reference gene:2505283788; PFAM: GTPase of unknown function; TIGRFAM: hydrogenase maturation GTPase HydF; small GTP-binding protein domain. (407 aa)    
Predicted Functional Partners:
AEH44382.1
Radical SAM domain protein; COGs: COG0502 Biotin synthase; InterPro IPR007197:IPR005244:IPR006638; KEGG: pth:PTH_0983 biotin synthase; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Biotin synthase and related enzymes; manually curated; IMG reference gene:2505283789; PFAM: Radical SAM superfamily; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydE.
   
 0.994
AEH44375.1
Biotin and thiamin synthesis associated; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR007197:IPR010722:IPR006638; KEGG: adg:Adeg_1241 thiamine biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Biotin and thiamin synthesis associated; IMG reference gene:2505283782; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydG; thiazole biosynthesis protein ThiH.
  
 0.942
AEH44377.1
Hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR013352:IPR004108:IPR003149:IPR017896:IPR 017900; KEGG: hor:Hore_06330 NADH dehydrogenase (ubiquinone) 75 kDa subunit; PFAM: hydrogenase large subunit domain protein; iron hydrogenase small subunit; PRIAM: Ferredoxin hydrogenase; SPTR: NADH dehydrogenase (Ubiquinone) 75 kDa subunit; TIGRFAM: hydrogenase, Fe-only; IMG reference gene:2505283784; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Iron hydrogenase small subunit; TIGRFAM: hydrogenase, Fe-only.
 
   
 0.872
AEH44380.1
COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterPro IPR004108:IPR017896:IPR017900; KEGG: tye:THEYE_A1726 hydrogenase; PFAM: hydrogenase large subunit domain protein; PRIAM: Ferredoxin hydrogenase; SPTR: Hydrogenase; IMG reference gene:2505283787; PFAM: Iron only hydrogenase large subunit, C-terminal domain; 4Fe-4S binding domain; TIGRFAM: hydrogenase, Fe-only.
 
     0.856
AEH44376.1
KEGG: ate:Athe_0168 putative transcriptional regulator, CopG family; SPTR: Putative uncharacterized protein; IMG reference gene:2505283783; TIGRFAM: putative iron-only hydrogenase system regulator.
 
     0.810
AEH44379.1
InterPro IPR003149; KEGG: she:Shewmr4_3251 iron hydrogenase, small subunit; PFAM: iron hydrogenase small subunit; SPTR: Iron hydrogenase, small subunit; IMG reference gene:2505283786; PFAM: Iron hydrogenase small subunit.
 
    0.785
AEH45232.1
Hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR006311:IPR013352:IPR004108:IPR003149:IPR 006058:IPR017900:IPR017909:IPR017896; KEGG: pth:PTH_0668 iron only hydrogenase large subunit; PFAM: hydrogenase large subunit domain protein; iron hydrogenase small subunit; PRIAM: Ferredoxin hydrogenase; SPTR: Iron only hydrogenase large subunit, C-terminal domain; TIGRFAM: hydrogenase, Fe-only; IMG reference gene:2505284680; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Iron hydrogenase small subunit; TIGRFAM: hydrogenase, Fe-only.
 
     0.771
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
   
    0.717
gpsA
NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; COGs: COG0240 Glycerol-3-phosphate dehydrogenase; InterPro IPR006168:IPR011128:IPR006109; KEGG: lbf:LBF_0334 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; SPTR: Glycerol-3-phosphate dehydrogenase [NAD(P)+]; IMG reference gene:2505284887; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
  
 0.708
AEH44911.1
COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR017900:IPR004089:IPR017896; KEGG: clj:CLJU_c20370 putative transcriptional regulator; PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; SPTR: Putative uncharacterized protein; IMG reference gene:2505284350; PFAM: Iron only hydrogenase large subunit, C-terminal domain; 4Fe-4S binding domain; Methyl-accepting chemotaxis protein (MCP) signaling domain.
 
     0.636
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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